Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity - Test2 - elhamkhani - TriplyDB

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

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Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases Interaction of JMJD6 with single-stranded RNA JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor Histone demethylases in chromatin biology and beyond Dynamics of H3K27me3 methylation and demethylation in plant development Epigenetic regulation by histone demethylases in hypoxia The role of histone demethylases in cancer therapy A peek into the complex realm of histone phosphorylation KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches Structural insights into a novel histone demethylase PHF8 Synthesis of 5-Hydroxyectoine from Ectoine: Crystal Structure of the Non-Heme Iron(II) and 2-Oxoglutarate-Dependent Dioxygenase EctD Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation Quaternary ammonium oxidative demethylation: X-ray crystallographic, resonance Raman, and UV-visible spectroscopic analysis of a Rieske-type demethylase Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases Ribosomal oxygenases are structurally conserved from prokaryotes to humans The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B Substituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases Structural analysis of human KDM5B guides histone demethylase inhibitor development IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives

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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

http://www.wikidata.org/entity/Q27646391

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@ast

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@en

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@nl

type

label

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@ast

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@en

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@nl

prefLabel

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@ast

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

@en

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

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Benoit M R Lienard

http://www.w3.org/2001/XMLSchema#string

Danica Butler

http://www.w3.org/2001/XMLSchema#string

Ewa S Pilka

http://www.w3.org/2001/XMLSchema#string

Johanna C Scheinost

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Kathryn L Kavanagh

http://www.w3.org/2001/XMLSchema#string

Michael Sundstrom

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Stanley S Ng

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87-91

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scholarly article

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552522

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10.1038/NATURE05971

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7149

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448

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Christopher J. Schofield

Frank von Delft

Michael A McDonough

Tomasz Borowski

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2007-07-05T00:00:00Z

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6246977

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1025319488

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17589501

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crystal structure