Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
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Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategyCrystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transportInsights to ligand binding to the monoamine transporters-from homology modeling to LeuBAT and dDATThe SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunctionVisualizing functional motions of membrane transporters with molecular dynamics simulationsHow LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transportersA conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.Neurotransmitter and psychostimulant recognition by the dopamine transporter.Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic ResiduesModeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueStructure of a prokaryotic virtual proton pump at 3.2 Å resolutionA competitive inhibitor traps LeuT in an open-to-out conformation.Structure and mechanism of an amino acid antiporterStructure and Mechanism of a Na+-Independent Amino Acid TransporterMolecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1The mechanism of sodium and substrate release from the binding pocket of vSGLTStructure and mechanism of the uracil transporter UraASubstrate specificity and ion coupling in the Na+/betaine symporter BetPMolecular basis of substrate-induced permeation by an amino acid antiporterInsights into transport mechanism from LeuT engineered to transport tryptophanX-ray structures of LeuT in substrate-free outward-open and apo inward-open statesBinding thermodynamics of a glutamate transporter homologStructure and mechanism of a glutamate-GABA antiporterArginine oscillation explains Na+ independence in the substrate/product antiporter CaiTCoupled ion binding and structural transitions along the transport cycle of glutamate transportersMolecular mechanism of ligand recognition by membrane transport protein, Mhp1Determinants of cation transport selectivity: Equilibrium binding and transport kineticsTransient formation of water-conducting states in membrane transportersAn efficient strategy for small-scale screening and production of archaeal membrane transport proteins in Escherichia coliAmphipols outperform dodecylmaltoside micelles in stabilizing membrane protein structure in the gas phase.Structural model of the anion exchanger 1 (SLC4A1) and identification of transmembrane segments forming the transport site.Conformational Changes in Two Inter-Helical Loops of Mhp1 Membrane Transporter.A refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints.Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanismsNavigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy.Structures of membrane proteins.Comprehensive analysis of the numbers, lengths and amino acid compositions of transmembrane helices in prokaryotic, eukaryotic and viral integral membrane proteins of high-resolution structure.Overcoming barriers to membrane protein structure determination.A gate-free pathway for substrate release from the inward-facing state of the Na⁺-galactose transporterSimulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family.
P2860
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P2860
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@ast
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@en
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@en-gb
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@nl
type
label
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@ast
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@en
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@en-gb
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@nl
prefLabel
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@ast
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@en
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@en-gb
Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter
@en
P2093
Halina T Norbertczak
John O'Reilly
Jonathan M Hadden
Kuakarun Krusong
Nicholas G Rutherford
Peter C J Roach
Peter J F Henderson
Ryan J Hope
Shun'ichi Suzuki
Shunsuke Yajima
P2860
P304
P3181
P356
10.1126/SCIENCE.1164440
P407
P577
2008-10-16T00:00:00Z