Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation - Test2 - elhamkhani - TriplyDB

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

http://www.wikidata.org/entity/Q27654230

about

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin OTULIN restricts Met1-linked ubiquitination to control innate immune signaling SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7 The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain Inducible SUMO modification of TANK alleviates its repression of TLR7 signalling cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)Signalling through the grapevine Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains Ubc13: the Lys63 ubiquitin chain building machine DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets Mass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein Ubiquitylation Poly-ubiquitination in TNFR1-mediated necroptosis Ubiquitin signaling in immune responses Ubiquitin modifications Cell Adhesion Molecules and Ubiquitination-Functions and Significance TNF biology, pathogenic mechanisms and emerging therapeutic strategies The paracaspase MALT1: biological function and potential for therapeutic inhibition Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting Expanding the ubiquitin code through post-translational modification NF-κB, the first quarter-century: remarkable progress and outstanding questions Protein degradation and the stress response Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation When ubiquitin meets NF-κB: a trove for anti-cancer drug development NF-κB regulation: lessons from structures Regulation of nuclear factor-κB in autoimmunity Death receptor-ligand systems in cancer, cell death, and inflammation Ubiquitin in the immune system The effects of TLR activation on T-cell development and differentiation The TLR and IL-1 signalling network at a glance NF-κB in inflammation and renal diseases Regulation of NF-κB by ubiquitination

P2860

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P2860

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

http://www.wikidata.org/entity/Q27654230

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Specific recognition of linear ...... rtant for NF-kappaB activation

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Felix Randow

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Masato Akutsu

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Masato Kawasaki

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Nobuhiro Suzuki

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Ryuichi Kato

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Simin Rahighi

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Stuart Bloor

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Tamami Uejima

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Tobias Kensche

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6

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136

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Soichi Wakatsuki

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24217415

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