A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
about
Ubiquitin modificationsTNF biology, pathogenic mechanisms and emerging therapeutic strategiesRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINRBR E3 ubiquitin ligases: new structures, new insights, new questionsRegulation of nuclear factor-κB in autoimmunityThe TLR and IL-1 signalling network at a glanceRegulation of NF-κB by ubiquitinationLinear ubiquitination signals in adaptive immune responsesA novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?Linear ubiquitination in immunityThe seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosisRegulation of tumour necrosis factor signalling: live or let dieThe paracaspase MALT1 mediates CARD14-induced signaling in keratinocytesThe linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Open reading frame 3 of genotype 1 hepatitis E virus inhibits nuclear factor-κappa B signaling induced by tumor necrosis factor-α in human A549 lung epithelial cellsPolyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosisProtein ubiquitination in lymphoid malignancies.Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection.Gene expression profile of peripheral blood monocytes: a step towards the molecular diagnosis of celiac disease?UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomesThe ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosisUSP18 negatively regulates NF-κB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms.Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.A20: linking a complex regulator of ubiquitylation to immunity and human diseaseInvolvement of A20 in the molecular switch that activates the non-canonical NF-кB pathwayTwo phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.Porcine Reproductive and Respiratory Syndrome Virus nsp1α Inhibits NF-κB Activation by Targeting the Linear Ubiquitin Chain Assembly Complex.Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance.Distinct phylogenetic relationships and biochemical properties of Arabidopsis ovarian tumor-related deubiquitinases support their functional differentiation.Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.Linear ubiquitination-mediated NF-κB regulation and its related disorders.Molecular control of the NEMO family of ubiquitin-binding proteins.RBR E3-ligases at workThe deubiquitinase A20 in immunopathology of autoimmune diseases.NF-κB and Rheumatoid Arthritis: Will Understanding Genetic Risk Lead to a Therapeutic Reward?Immune diseases caused by mutations in kinases and components of the ubiquitin system.
P2860
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P2860
A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@ast
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en-gb
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@nl
type
label
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@ast
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en-gb
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@nl
prefLabel
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@ast
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en-gb
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@nl
P2093
P2860
P3181
P356
P1433
P1476
A20 inhibits LUBAC-mediated NF ...... n chains via its zinc finger 7
@en
P2093
Isabelle Carpentier
Kelly Verhelst
Laura Meloni
Lynn Verstrepen
Marja Kreike
Tobias Kensche
P2860
P304
P3181
P356
10.1038/EMBOJ.2012.240
P407
P577
2012-10-03T00:00:00Z