A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms
about
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwindingThe molecular topography of silenced chromatin in Saccharomyces cerevisiaeA Taz1- and Microtubule-Dependent Regulatory Relationship between Telomere and Centromere Positions in Bouquet Formation Secures Proper Meiotic DivisionsStructural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNAEnd-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1.The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.PRL-3 promotes telomere deprotection and chromosomal instability.Nontelomeric role for Rap1 in regulating metabolism and protecting against obesity.Epigenetics in Saccharomyces cerevisiae.Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase statusIdentification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombeFission yeast Cactin restricts telomere transcription and elongation by controlling Rap1 levelsTpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1.Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast.Human Rap1 modulates TRF2 attraction to telomeric DNA.Minishelterins separate telomere length regulation and end protection in fission yeastHuman Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomereComplex interactions between the DNA-damage response and mammalian telomeres.Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins.A higher-order entity formed by the flexible assembly of RAP1 with TRF2.TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.The shelterin complex and hematopoiesis.Telomerase and telomere-associated proteins: structural insights into mechanism and evolution.Fission yeast shelterin regulates DNA polymerases and Rad3(ATR) kinase to limit telomere extension.Decoding telomere protein Rap1: Its telomeric and nontelomeric functions and potential implications in diabetic cardiomyopathy.Variants of the Sir4 Coiled-Coil Domain Improve Binding to Sir3 for Heterochromatin Formation in Saccharomyces cerevisiae.Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity.Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.Identification of a transcriptional activation domain in yeast repressor activator protein 1 (Rap1) using an altered DNA-binding specificity variant.Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks.
P2860
Q24316035-5C92998F-ED5A-40DC-B06C-A3EF05D9D9FEQ24605397-9CD82243-9E73-43BF-8C90-2673A1E2F6D9Q27307940-5DA10445-125B-4109-85AE-657501C7CC39Q27673259-4A1D4CF2-252E-4713-BCF4-E9D839243963Q27675973-F615749C-081F-4E11-BF79-E200C4D53D9FQ27936985-9448D5DF-1855-47D9-9908-F1ECBC25EA5AQ30276142-F1060A0B-4DD0-4389-9288-79EBF7F40368Q33878962-D03592D1-67A0-4D89-9CEC-DDA3DFC0A388Q33924629-BF222D8B-1ECE-44BB-9DFB-B5D0EC4C511FQ34037400-A73CD470-1A9D-49E3-B87F-B5315D93DFAAQ34420523-A04AAF20-4C7A-4BB4-AC49-29EA1DA4E35CQ34469940-DACA858C-7CFE-47A2-8E48-861AA3BD5B49Q34924069-BCD18538-1285-4D90-BFA9-DA30B67E18F4Q34980899-7F0EC3C8-419A-4226-9AE8-39F4266154D5Q35082669-9C53D4A8-861C-4F3C-85BE-21783A0102B3Q35171575-817A4388-C93A-4E07-8AF6-404CF32B2B95Q35660631-591F3D4C-5FA3-49B1-B1E3-F9FCB3E08DCFQ36451842-849D6ED9-1230-4377-872B-F60595BAC6FEQ36539673-7B9AD7C1-AE59-4AF8-B1C8-58BD9190303BQ36564417-FC853299-B3AB-4978-9E20-4FFD03340E26Q36627966-5D473CD5-397F-4754-A115-15D428418986Q36670262-7E5814DD-0E04-4CD7-BDA0-CC2492FD637BQ36867317-143F6C94-669E-4933-942B-9818EEDA71EBQ37975743-49A0CE61-797E-4E13-8195-7EC6990AB56AQ42131808-06204656-B44B-4868-9FFB-20B5E7551078Q42278533-C1A6585F-9FD8-4AB8-A1F3-730FD20FEA3EQ42292336-8FC3CB91-3230-4FDB-9ABE-3ABB71B8104AQ42652989-3BD71B27-AB34-46DD-87EA-13A94BF0CA1CQ47379576-BB25C0EF-FCF5-4214-8A04-4AEE5DAC77FCQ47379585-96C231F0-1859-45DF-A33E-3362B48B2662Q51004498-697E6C2F-F697-4A37-8BCC-A8AC59DBD479Q55511176-425569F1-57CF-464B-8BDA-2EA824D86314
P2860
A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A conserved motif within RAP1 ...... ulation in different organisms
@ast
A conserved motif within RAP1 ...... ulation in different organisms
@en
A conserved motif within RAP1 ...... ulation in different organisms
@nl
type
label
A conserved motif within RAP1 ...... ulation in different organisms
@ast
A conserved motif within RAP1 ...... ulation in different organisms
@en
A conserved motif within RAP1 ...... ulation in different organisms
@nl
prefLabel
A conserved motif within RAP1 ...... ulation in different organisms
@ast
A conserved motif within RAP1 ...... ulation in different organisms
@en
A conserved motif within RAP1 ...... ulation in different organisms
@nl
P2093
P2860
P50
P3181
P356
P1476
A conserved motif within RAP1 ...... ulation in different organisms
@en
P2093
Hisayo Tsujii
Hong Zheng
Hong-Yu Hu
Junko Kanoh
Pascal Damay
Sandy Chang
Yuting Yang
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1974
P577
2011-02-01T00:00:00Z
P5875
P6179
1030013618