ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
about
The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changesMre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairDNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease ActivitiesStructure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signalingATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signalingDNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae.Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairTel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand BreaksShared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallographyEnd resection at double-strand breaks: mechanism and regulation.Autoinhibition of bacteriophage T4 Mre11 by its C-terminal domain.Recognition and repair of chemically heterogeneous structures at DNA endsCohesin without cohesion: a novel role for Pds5 in Saccharomyces cerevisiae.Biochemical and Functional Characterization of the NurA-HerA Complex from Deinococcus radiodurans.Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil DomainDisruption of the bacteriophage T4 Mre11 dimer interface reveals a two-state mechanism for exonuclease activityCohesin codes - interpreting chromatin architecture and the many facets of cohesin function.ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complexProcessing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET.Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins.Condensin: crafting the chromosome landscape.Repair of double-strand breaks by end joining.The bacterial chromosome: architecture and action of bacterial SMC and SMC-like complexes.The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once.Structural studies of DNA end detection and resection in homologous recombination.ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.Metallophosphoesterases: structural fidelity with functional promiscuity.Coupling end resection with the checkpoint response at DNA double-strand breaks.Eukaryotic Rad50 functions as a rod-shaped dimer.Functions and regulation of the MRX complex at DNA double-strand breaks.Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.A network of allosterically coupled residues in the bacteriophage T4 Mre11-Rad50 complexStructure of the catalytic domain of Mre11 from Chaetomium thermophilum.Coiled-coils: The long and short of it.The wobble nucleotide-excising anticodon nuclease RloC is governed by the zinc-hook and DNA-dependent ATPase of its Rad50-like region.Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites.
P2860
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P2860
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@ast
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@en
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@nl
type
label
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@ast
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@en
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@nl
prefLabel
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@ast
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@en
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@nl
P2860
P50
P3181
P356
P1476
ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
@en
P2860
P304
P3181
P356
10.1093/NAR/GKR749
P407
P577
2012-01-01T00:00:00Z