Fragment deconstruction of small, potent factor Xa inhibitors: exploring the superadditivity energetics of fragment linking in protein-ligand complexes

Fragment deconstruction of small, potent factor Xa inhibitors: exploring the superadditivity energetics of fragment linking in protein-ligand complexes

Item
http://www.wikidata.org/entity/Q27676351
Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein InterfaceCreating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug designCombinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization.Ligand-induced protein mobility in complexes of carbonic anhydrase II and benzenesulfonamides with oligoglycine chainsA fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.Novel 2-aminobenzamides as potential orally active antithrombotic agents.Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases.Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors.Protein-Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background-Free Amidation Reaction.Impact of a Central Scaffold on the Binding Affinity of Fragment Pairs Isolated from DNA-Encoded Self-Assembling Chemical Libraries.Novel Mcl-1/Bcl-2 dual inhibitors created by the structure-based hybridization of drug-divided building blocks and a fragment deconstructed from a known two-face BH3 mimetic.Pairwise binding competition experiments for sorting hub-protein/effector interaction hierarchy and simultaneous equilibria
P2860

Fragment deconstruction of small, potent factor Xa inhibitors: exploring the superadditivity energetics of fragment linking in protein-ligand complexes

Item
http://www.wikidata.org/entity/Q27676351
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@ast
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@en
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@nl
type
label
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@ast
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@en
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@nl
prefLabel
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@ast
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@en
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Fragment deconstruction of sma ...... ng in protein-ligand complexes
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698