A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
about
Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α'.Insights into the Impact of Linker Flexibility and Fragment Ionization on the Design of CK2 Allosteric Inhibitors: Comparative Molecular Dynamics Simulation Studies.Second-generation CK2α inhibitors targeting the αD pocket.
P2860
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
A fragment-based approach lead ...... lective CK2 inhibitor CAM4066.
@en
type
label
A fragment-based approach lead ...... lective CK2 inhibitor CAM4066.
@en
prefLabel
A fragment-based approach lead ...... lective CK2 inhibitor CAM4066.
@en
P2093
P2860
P50
P1476
A fragment-based approach lead ...... lective CK2 inhibitor CAM4066.
@en
P2093
Claudia De Fusco
Hannah F Sore
Kathy Hadje Georgiou
Marko Hyvönen
P2860
P304
P356
10.1016/J.BMC.2017.04.037
P407
P577
2017-04-30T00:00:00Z