Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis

Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis

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http://www.wikidata.org/entity/Q27677374
Kinetic features of L,D-transpeptidase inactivation critical for β-lactam antibacterial activityBinding and processing of β-lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis.Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.Non-classical transpeptidases yield insight into new antibacterialsGenetic characterization of mycobacterial L,D-transpeptidases.Transcriptional Profiling of Coxiella burnetii Reveals Extensive Cell Wall Remodeling in the Small Cell Variant Developmental Form.Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus.Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.Acyl acceptor recognition by Enterococcus faecium L,D-transpeptidase Ldtfm.Toward antituberculosis drugs: in silico screening of synthetic compounds against Mycobacterium tuberculosisl,d-transpeptidase 2Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactamsThe Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.Differential flap dynamics in l,d-transpeptidase2 from mycobacterium tuberculosis revealed by molecular dynamics.Simulating the inhibition reaction of Mycobacterium tuberculosis L,D-transpeptidase 2 by carbapenems.Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2.Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Futureand β-Lactams: Emerging Insights and Potential Opportunities
P2860

Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis

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http://www.wikidata.org/entity/Q27677374
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2013 nî lūn-bûn
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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2013 թվականի մայիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
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Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
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Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
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type
label
Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
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Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
@en
Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
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prefLabel
Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
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Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
@en
Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P6179
P698
P921
P932
P356
P1433
P1476
Crystal structure of L,D-trans ...... nst Mycobacterium tuberculosis
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P6179
P698
P921
P932