Crystal structure of the cataract-causing P23T γD-crystallin mutant
about
Lens β-crystallins: the role of deamidation and related modifications in aging and cataract.Exome sequencing identifies novel and recurrent mutations in GJA8 and CRYGD associated with inherited cataract.Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.Wild-type human γD-crystallin promotes aggregation of its oxidation-mimicking, misfolding-prone W42Q mutant.Aggregation of Trp > Glu point mutants of human gamma-D crystallin provides a model for hereditary or UV-induced cataract.The self assembly of proteins; probing patchy protein interactions.
P2860
Crystal structure of the cataract-causing P23T γD-crystallin mutant
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@ast
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@en
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@nl
type
label
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@ast
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@en
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@nl
prefLabel
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@ast
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@en
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@nl
P2860
P50
P356
P1433
P1476
Crystal structure of the cataract-causing P23T γD-crystallin mutant
@en
P2093
Fangling Ji
P2860
P304
P356
10.1002/PROT.24321
P407
P577
2013-09-01T00:00:00Z