The structure of the FANCM–MHF complex reveals physical features for functional assembly - Test2 - elhamkhani - TriplyDB

The structure of the FANCM–MHF complex reveals physical features for functional assembly

The structure of the FANCM–MHF complex reveals physical features for functional assembly

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Structural peculiarities of the (MHF1-MHF2)4 octamer provide a long DNA binding patch to anchor the MHF-FANCM complex to chromatin: a solution SAXS study Functions and regulation of the multitasking FANCM family of DNA motor proteins Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly Multiple interactions of the intrinsically disordered region between the helicase and nuclease domains of the archaeal Hef protein The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.The 68-kDa telomeric repeat binding factor 1 (TRF1)-associated protein (TAP68) interacts with and recruits TRF1 to the spindle pole during mitosis Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling MHF1 plays Fanconi anaemia complementation group M protein (FANCM)-dependent and FANCM-independent roles in DNA repair and homologous recombination in plants.The centromere: epigenetic control of chromosome segregation during mitosis Selective modulation of the functions of a conserved DNA motor by a histone fold complex.Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation miR146a-mediated targeting of FANCM during inflammation compromises genome integrity.Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP).Functions of the centromere and kinetochore in chromosome segregation.Two-way communications between ubiquitin-like modifiers and DNA.Stress and DNA repair biology of the Fanconi anemia pathway Middle region of FancM interacts with Mhf and Rmi1 in silkworms, a species lacking the Fanconi anaemia (FA) core complex.Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers.MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination.Regulation of mitotic recombination between DNA repeats in centromeres.FANCM:FAAP24 and APITD1:STRA13 bind ICL-DNA

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

http://www.wikidata.org/entity/Q27678576

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2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

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2012年論文

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2012年论文

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name

The structure of the FANCM–MHF complex reveals physical features for functional assembly

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

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type

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

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prefLabel

The structure of the FANCM–MHF complex reveals physical features for functional assembly

@ast

The structure of the FANCM–MHF complex reveals physical features for functional assembly

@en

The structure of the FANCM–MHF complex reveals physical features for functional assembly

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Nature Communications

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The structure of the FANCM–MHF complex reveals physical features for functional assembly

@en

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Changjiang Jin

http://www.w3.org/2001/XMLSchema#string

Lingluo Chu

http://www.w3.org/2001/XMLSchema#string

Maikun Teng

http://www.w3.org/2001/XMLSchema#string

Shali Qi

http://www.w3.org/2001/XMLSchema#string

Xu Li

http://www.w3.org/2001/XMLSchema#string

Xuebiao Yao

http://www.w3.org/2001/XMLSchema#string

Yuyong Tao

http://www.w3.org/2001/XMLSchema#string

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Crystal structure of the nucleosome core particle at 2.8 A resolution

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability

MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM

The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres

Mutations of the SLX4 gene in Fanconi anemia

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

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10.1038/NCOMMS1779

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2012-04-17T00:00:00Z

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1041845580

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22510687

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3646547

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