MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM
about
Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeastCtIP is required to initiate replication-dependent interstrand crosslink repairCENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like foldFAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathwayStructural peculiarities of the (MHF1-MHF2)4 octamer provide a long DNA binding patch to anchor the MHF-FANCM complex to chromatin: a solution SAXS studyA ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair networkBreast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairMolecular pathogenesis and clinical management of Fanconi anemiaHow SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair PathwayFunctions and regulation of the multitasking FANCM family of DNA motor proteinsExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapyThe Fanconi anemia pathway and DNA interstrand cross-link repairLearning from a paradox: recent insights into Fanconi anaemia through studying mouse modelsFanconi anemia and the cell cycle: new perspectives on aneuploidyDefining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasomeThe structure of the FANCM–MHF complex reveals physical features for functional assemblyStructure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage responseStructural insights into the functions of the FANCM-FAAP24 complex in DNA repairThe MHF complex senses branched DNA by binding a pair of crossover DNA duplexesThe DNA Damage Response: Making It Safe to Play with KnivesMechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3Fancf-deficient mice are prone to develop ovarian tumoursForkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage responseThe RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteinsThe fission yeast FANCM ortholog directs non-crossover recombination during meiosisExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.A new histone at the centromere?Multiple interactions of the intrinsically disordered region between the helicase and nuclease domains of the archaeal Hef proteinA new nuclease member of the FAN club.Fanconi anemia proteins and their interacting partners: a molecular puzzleThe histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint responseThe genetic and biochemical basis of FANCD2 monoubiquitinationChronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways.Fanconi anemia core complex gene promoters harbor conserved transcription regulatory elements.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.The centromere: chromatin foundation for the kinetochore machinery.The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair.Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
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MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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name
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@ast
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en-gb
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@nl
type
label
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@ast
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en-gb
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@nl
prefLabel
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@ast
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en-gb
MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@nl
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MHF1-MHF2, a histone-fold-cont ...... nconi anemia pathway via FANCM
@en
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Amom Ruhikanta Meetei
Andrew J Pierce
Aristidis Sachpatzidis
Chang-hu Du
Dorina Saro
Kebola Wahengbam
Michael W Killen
Patrick Sung
Thiyam Ramsing Singh
Xiao-Feng Zheng
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10.1016/J.MOLCEL.2010.01.036
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2010-03-01T00:00:00Z