Mutations of the SLX4 gene in Fanconi anemia - Test2 - elhamkhani - TriplyDB

Mutations of the SLX4 gene in Fanconi anemia

Mutations of the SLX4 gene in Fanconi anemia

http://www.wikidata.org/entity/Q24628650

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The mouse genetics toolkit: revealing function and mechanism Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis CtIP is required to initiate replication-dependent interstrand crosslink repair FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway Structural peculiarities of the (MHF1-MHF2)4 octamer provide a long DNA binding patch to anchor the MHF-FANCM complex to chromatin: a solution SAXS study Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions Molecular pathogenesis and clinical management of Fanconi anemia Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress Mechanisms of interstrand DNA crosslink repair and human disorders Interplay between Fanconi anemia and homologous recombination pathways in genome integrity Update of the human and mouse Fanconi anemia genes The Fanconi anemia pathway and DNA interstrand cross-link repair Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae Mechanism and regulation of incisions during DNA interstrand cross-link repair Pathways for repairing and tolerating the spectrum of oxidative DNA lesions Diseases associated with defective responses to DNA damage DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy Diagnosis of Fanconi Anemia: Chromosomal Breakage Analysis The structure of the FANCM–MHF complex reveals physical features for functional assembly How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.Budding Yeast SLX4 Contributes to the Appropriate Distribution of Crossovers and Meiotic Double-Strand Break Formation on Bivalents During Meiosis.Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.Role of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in budding yeast SUMO-mediated regulation of DNA damage repair and responses XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4 Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease PALB2: the hub of a network of tumor suppressors involved in DNA damage responses Fancf-deficient mice are prone to develop ovarian tumours Uncoupling of transcription and translation of Fanconi anemia (FANC) complex proteins during spermatogenesis Fanconi anaemia and the repair of Watson and Crick DNA crosslinks Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia Advances in understanding the complex mechanisms of DNA interstrand cross-link repair Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse A never-ending story: the steadily growing family of the FA and FA-like genes Sequencing analysis of SLX4/FANCP gene in Italian familial breast cancer cases.Role of Genetic Factors in the Pathogenesis of Radial Deficiencies in Humans.Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients.

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P2860

Mutations of the SLX4 gene in Fanconi anemia

http://www.wikidata.org/entity/Q24628650

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Mutations of the SLX4 gene in Fanconi anemia

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Nature Genetics

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Mutations of the SLX4 gene in Fanconi anemia

@en

P2093

Francis P Lach

http://www.w3.org/2001/XMLSchema#string

Helmut Hanenberg

http://www.w3.org/2001/XMLSchema#string

Rohini Desetty

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Yonghwan Kim

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P2860

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

How the fanconi anemia pathway guards the genome

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

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scholarly article

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1644435

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10.1038/NG.750

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2

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43

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Agata Smogorzewska

Arleen D. Auerbach

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2011-02-01T00:00:00Z

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49760523

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1006887255

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21240275

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3345287

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