Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene
about
Structure and Stereospecificity of the Dehydratase Domain from the Terminal Module of the Rifamycin Polyketide SynthaseStructural and functional studies of atrans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective α- and β-ketoreductionMycocerosic acid synthase exemplifies the architecture of reducing polyketide synthasesDomain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferaseArchitecture of the polyketide synthase module: surprises from electron cryo-microscopyRecent advances in the elucidation of enzymatic function in natural product biosynthesisTrichophycin A, a Cytotoxic Linear Polyketide Isolated from a Trichodesmium thiebautii BloomBiosynthesis of colabomycin E, a new manumycin-family metabolite, involves an unusual chain-length factor.Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.Polyketide intermediate mimics as probes for revealing cryptic stereochemistry of ketoreductase domains.Polyketide stereocontrol: a study in chemical biology.Uncovering the structures of modular polyketide synthases.Stereocontrol within polyketide assembly lines.The structural biology of biosynthetic megaenzymes.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies.Structural rearrangements of a polyketide synthase module during its catalytic cycle.Structure of a modular polyketide synthase.Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases.Tylosin polyketide synthase module 3: stereospecificity, stereoselectivity and steady-state kinetic analysis of β-processing domains via diffusible, synthetic substrates.The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide.Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates.Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT Reveals the Biosynthetic Pathway of the Antifungal Thailandin Compounds with Unusual Butylmalonyl-CoA Extender Units.Advance in Research on Mycobacterium tuberculosis FabG4 and Its Inhibitor.Structural and Functional Trends in Dehydrating Bimodules from trans-Acyltransferase Polyketide Synthases.
P2860
Q27680680-59C0D584-F494-4FED-B708-70EC0E94622CQ27682252-D83A89EB-CEB8-4155-8286-37D01F4FA83CQ27704254-4B617B74-3F8B-4B96-9C5D-2665021E8FA8Q27728317-FFA15169-5C01-4056-ADF4-90AC06BF35FAQ28081578-20F06D57-62B1-4013-B155-4C1DC354FFC5Q28087244-FE938A04-142D-4C22-A7B2-02C2A4D98E68Q28817330-973703CE-3789-49DD-96E7-065732A23355Q35170571-2D24B4E9-A0ED-4CE9-9652-67CE56030DD7Q35206279-404C8F65-E5DB-4973-B974-571C8CF5DB56Q35316202-261DB9E9-6690-4341-B1C1-FD8788CD73B3Q37672851-9149CB63-E50A-47D4-AEE2-37BC3113BA21Q38259700-A684B573-23E2-4DE2-9C4A-D8242431995DQ38264057-67A125AB-053E-478D-A655-34984BC07A02Q38568948-ED7CCA54-5A36-44BF-87E2-851A84236426Q38629855-70B0C364-E031-485A-B88E-E74BFA95055BQ38792678-B01F2527-FB36-4BB9-A7CC-5D24A2EF54CAQ41456081-69C63ED6-4415-4F40-B478-245B5A2012E4Q41608053-F88B8755-A1E8-465F-A789-CC8A0C01E790Q41968771-C2F2B897-38E3-42D3-B2AB-D2FC10371216Q42577561-4CCCA98C-4203-4CE7-8319-CE160B3E9FE9Q42764696-E4C620BB-3BE9-4517-8816-D4F94CF1064EQ47694075-BCA6C8A0-FE99-43BD-A1A1-6CF7423E6BCCQ52329344-2A5B31B5-11B6-488B-8460-000536F5DBD1Q52676787-F2C1A07C-6C48-4EE5-89B3-051F2CC8CEF6Q55311481-0E2F05CA-4C90-4F1A-B717-F1FF059785BDQ55492973-4406E83F-5185-41FE-8AA3-A0196ED62F83
P2860
Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural and Stereochemical ...... the Generation of a cis-Alkene
@ast
Structural and Stereochemical ...... the Generation of a cis-Alkene
@en
Structural and Stereochemical ...... the Generation of a cis-Alkene
@nl
type
label
Structural and Stereochemical ...... the Generation of a cis-Alkene
@ast
Structural and Stereochemical ...... the Generation of a cis-Alkene
@en
Structural and Stereochemical ...... the Generation of a cis-Alkene
@nl
prefLabel
Structural and Stereochemical ...... the Generation of a cis-Alkene
@ast
Structural and Stereochemical ...... the Generation of a cis-Alkene
@en
Structural and Stereochemical ...... the Generation of a cis-Alkene
@nl
P2093
P2860
P1476
Structural and stereochemical ...... the generation of a cis-alkene
@en
P2093
Galina Florova
Janet L Smith
Jonathan R Whicher
Kancharla Papireddy
Shilah A Bonnett
P2860
P304
P356
10.1016/J.CHEMBIOL.2013.04.014
P577
2013-06-01T00:00:00Z