E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1 - Test2 - elhamkhani - TriplyDB

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

http://www.wikidata.org/entity/Q27679710

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Ubc13: the Lys63 ubiquitin chain building machine E2 enzymes: more than just middle men Role of Deubiquitinating Enzymes in DNA Repair Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 Deubiquitinating enzymes as oncotargets Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1 The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization PTEN regulates RPA1 and protects DNA replication forks.OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer.Enzymatic Analysis of PTEN Ubiquitylation by WWP2 and NEDD4-1 E3 Ligases Mechanisms for regulating deubiquitinating enzymes.The emerging roles of deubiquitylating enzymes (DUBs) in the TGFβ and BMP pathways.DUBs, the regulation of cell identity and disease.Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway.Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future.Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells.Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions.Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest).A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme.Simultaneous detection of distinct ubiquitin chain topologies by 19F NMR.OTUB1 suppresses mTOR complex 1 (mTORC1) activity by deubiquitinating the mTORC1 inhibitor DEPTOR.A Tunable Brake for HECT Ubiquitin Ligases.Otubain 1: a non-canonical deubiquitinase with an emerging role in cancer

P2860

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P2860

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

http://www.wikidata.org/entity/Q27679710

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@ast

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@en

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@nl

type

label

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@ast

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@en

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@nl

prefLabel

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@ast

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@en

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@nl

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P1433

Nature Structural & Molecular Biology

P1476

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

@en

P2093

Anthony T DiBello

http://www.w3.org/2001/XMLSchema#string

Catherine M Guzzo

http://www.w3.org/2001/XMLSchema#string

Patrick M Lombardi

http://www.w3.org/2001/XMLSchema#string

Reuven Wiener

http://www.w3.org/2001/XMLSchema#string

Xiangbin Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

NIH Image to ImageJ: 25 years of image analysis

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1

Structural basis and specificity of human otubain 1-mediated deubiquitination

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

Defining the human deubiquitinating enzyme interaction landscape

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

Otubains: a new family of cysteine proteases in the ubiquitin pathway

Processing of X-ray diffraction data collected in oscillation mode

Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugates

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1033-1039

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scholarly article

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1016017

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P356

10.1038/NSMB.2655

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P433

9

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P478

20

http://www.w3.org/2001/XMLSchema#string

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Michael J. Matunis

Cynthia Wolberger

P577

2013-08-18T00:00:00Z

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255975373

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1052929981

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P698

23955022

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P921

structural biology

P932

3941643

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