Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1
about
OTUB1 modulates c-IAP1 stability to regulate signalling pathwaysDUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workDeubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1Deubiquitinating enzymes as oncotargetsOTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme FunctionE2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1Ubiquitylation, neddylation and the DNA damage responseFIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Proteomic profile of pre - B2 lymphoblasts from children with acute lymphoblastic leukemia (ALL) in relation with the translocation (12; 21)Systematic analysis of the physiological importance of deubiquitinating enzymes.The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells.USP11 regulates p53 stability by deubiquitinating p53.OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.Coxsackievirus-induced miR-21 disrupts cardiomyocyte interactions via the downregulation of intercalated disk components.OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer.Regulation of the DNA damage response by ubiquitin conjugation.The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-MycThe human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistanceThe Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.OTUB1 promotes tumor invasion and predicts a poor prognosis in gastric adenocarcinoma.OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer.Ubiquitin at the crossroad of cell death and survival.TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK-STAT signaling pathway.Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.Distinct phylogenetic relationships and biochemical properties of Arabidopsis ovarian tumor-related deubiquitinases support their functional differentiation.Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy.Deubiquitylating enzymes and DNA damage response pathways.Regulation of proteolysis by human deubiquitinating enzymes.Deubiquitylases from genes to organism.DUBs, the regulation of cell identity and disease.Copy number variation in archival melanoma biopsies versus benign melanocytic lesions.Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint.Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondriaSilencing of OTUB1 inhibits migration of human glioma cells in vitro.
P2860
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P2860
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@ast
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en-gb
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@nl
type
label
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@ast
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en-gb
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@nl
prefLabel
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@ast
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en-gb
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@nl
P2093
P2860
P3181
P356
P1433
P1476
Positive regulation of p53 sta ...... biquitinating enzyme Otubain 1
@en
P2093
Kishore B Challagundla
Mu-Shui Dai
Xiao-Xin Sun
P2860
P304
P3181
P356
10.1038/EMBOJ.2011.434
P407
P577
2012-02-01T00:00:00Z