Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1 - Test2 - elhamkhani - TriplyDB

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

http://www.wikidata.org/entity/Q24310203

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The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80 Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3 Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function Assembly, analysis and architecture of atypical ubiquitin chains The mechanism of OTUB1-mediated inhibition of ubiquitination Structural and biochemical studies of the open state of Lys48-linked diubiquitin E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1 MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes.FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1 The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.Plasmodium falciparum OTU-like cysteine protease (PfOTU) is essential for apicoplast homeostasis and associates with noncanonical role of Atg8 Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs Recent advances in polyubiquitin chain recognition.Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin.Ubiquitin makes its mark on immune regulation.Ubiquitin-proteasome pathway and cellular responses to oxidative stress.OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer.OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.A20: linking a complex regulator of ubiquitylation to immunity and human disease OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks.OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer.Distinct phylogenetic relationships and biochemical properties of Arabidopsis ovarian tumor-related deubiquitinases support their functional differentiation.PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications.Regulation of proteolysis by human deubiquitinating enzymes.Deubiquitylases from genes to organism.Mechanisms for regulating deubiquitinating enzymes.The emerging roles of deubiquitylating enzymes (DUBs) in the TGFβ and BMP pathways.Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice.Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.Activity-based probes for the ubiquitin conjugation-deconjugation machinery: new chemistries, new tools, and new insights.

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P2860

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

http://www.wikidata.org/entity/Q24310203

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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prefLabel

Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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Evidence for bidentate substra ...... nkage specificity of otubain 1

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P932

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P356

J.JMB.2008.12.085

P1433

Journal of Molecular Biology

P1476

Evidence for bidentate substra ...... nkage specificity of otubain 1

@en

P2093

Cecile M Pickart

http://www.w3.org/2001/XMLSchema#string

David Fushman

http://www.w3.org/2001/XMLSchema#string

Eric M Cooper

http://www.w3.org/2001/XMLSchema#string

Keith D Wilkinson

http://www.w3.org/2001/XMLSchema#string

Luming Yin

http://www.w3.org/2001/XMLSchema#string

Ming-Yih Lai

http://www.w3.org/2001/XMLSchema#string

Robert E Cohen

http://www.w3.org/2001/XMLSchema#string

Seth Dickey

http://www.w3.org/2001/XMLSchema#string

Tao Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

Crystal structure of human otubain 2.

Structural basis and specificity of human otubain 1-mediated deubiquitination

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

UBPY: a growth-regulated human ubiquitin isopeptidase.

Recognition of the polyubiquitin proteolytic signal

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

Otubains: a new family of cysteine proteases in the ubiquitin pathway

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1011-23

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scholarly article

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1004323

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10.1016/J.JMB.2008.12.085

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P407

P433

4

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P478

386

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Cynthia Wolberger

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2009-03-06T00:00:00Z

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24002121

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P698

19211026

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P921

protein K48-linked deubiquitination

OTU deubiquitinase, ubiquitin aldehyde binding 1

P932

2682458

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