Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase

Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase

Item
http://www.wikidata.org/entity/Q27681323
Prodrugs of phosphonates and phosphates: crossing the membrane barrierTransition-state inhibitors of purine salvage and other prospective enzyme targets in malariaSynthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine PhosphoribosyltransferasesPurine import into malaria parasites as a target for antimalarial drug development.Crystal structures and inhibition of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase.From crystal to compound: structure-based antimalarial drug discovery.Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine and a Five-Membered Heterocycle as Selective Inhibitors of Plasmodial 6-Oxopurine Phosphoribosyltransferases.Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.Kinetic Isotope Effects and Transition State Structure for Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from Plasmodium falciparum.Structural and dynamical correlations in PfHGXPRT oligomers: A molecular dynamics simulation study.Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
P2860

Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase

Item
http://www.wikidata.org/entity/Q27681323
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@ast
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@en
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@nl
type
label
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@ast
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@en
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@nl
prefLabel
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@ast
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@en
Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
@nl
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Acyclic Immucillin Phosphonate ...... hine Phosphoribosyltransferase
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P2093
P2860
P304
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P3181
P356
10.1016/J.CHEMBIOL.2012.04.012
P433
P478
P50
P577
P5875
P698
P921
P932