Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
about
Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNAFail-safe transcription termination: Because one is never enoughSurprises in the 3'-end: 'U' can decide too!The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human DiseaseThreading the barrel of the RNA exosomeProcessing of preribosomal RNA in Saccharomyces cerevisiaeRRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substratesStructure of an Rrp6–RNA exosome complex bound to poly(A) RNAA PilT N-terminus domain protein SSO1118 from hyperthemophilic archaeon Sulfolobus solfataricus P2RNA degradation paths in a 12-subunit nuclear exosome complexCryoEM structure of yeast cytoplasmic exosome complexRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeThe exosome complex establishes a barricade to erythroid maturationThe exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathwayMechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathwayTrifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational statesHow cryo-electron microscopy and X-ray crystallography complement each other.EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia.Promiscuous RNA binding by Polycomb repressive complex 2.The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.Structured RNAs that evade or confound exonucleases: function follows form.Regulatory mechanisms of RNA function: emerging roles of DNA repair enzymes.Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome.RNA stimulates Aurora B kinase activity during mitosis.Comprehensive classification of the PIN domain-like superfamilyIntegrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery.The mitochondrial RNA landscape of Saccharomyces cerevisiaeThe human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decayThe exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae.Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-productElements of the cellular metabolic structure.The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.The Helicase Activity of Ribonuclease R Is Essential for Efficient Nuclease ActivityDIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts.Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complexCooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.A strategy for dissecting the architectures of native macromolecular assembliesThe roles of 3'-exoribonucleases and the exosome in trypanosome mRNA degradation.Exosome-bound WD repeat protein Monad inhibits breast cancer cell invasion by degrading amphiregulin mRNA
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P2860
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
description
2013 nî lūn-bûn
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@ast
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@en
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@nl
type
label
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@ast
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@en
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@nl
prefLabel
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@ast
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@en
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@nl
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P1433
P1476
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex
@en
P2093
Debora Lika Makino
Marc Baumgärtner
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P2888
P3181
P356
10.1038/NATURE11870
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P50
P577
2013-03-07T00:00:00Z
P6179
1018452167