De novo protein design: fully automated sequence selection
about
Computational design of a PDZ domain peptide inhibitor that rescues CFTR activitySampling realistic protein conformations using local structural biasExperimental illumination of a fitness landscapeDesign of a Novel Globular Protein Fold with Atomic-Level AccuracyComputational enzyme design approaches with significant biological outcomes: progress and challengesFundamental challenges in mechanistic enzymology: progress toward understanding the rate enhancements of enzymesSearching sequence space for protein catalystsThe crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activityA smoothed backbone-dependent rotamer library for proteins derived from adaptive kernel density estimates and regressionsParadigms for computational nucleic acid designLessons from the lysozyme of phage T4High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein designComputational design of Candida boidinii xylose reductase for altered cofactor specificityA designed protein as experimental model of primordial foldingBalancing solvation and intramolecular interactions: toward a consistent generalized Born force fieldDesign of protein-ligand binding based on the molecular-mechanics energy modelSolution structure of a de novo protein from a designed combinatorial libraryNative protein sequences are close to optimal for their structuresRosettaDesign server for protein designTripeptide analysis of protein structures.Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design.The interface of protein structure, protein biophysics, and molecular evolutionProtein design: toward functional metalloenzymesFlow-Based Single Cell Deposition for High-Throughput Screening of Protein LibrariesFolding and Stabilization of Native-Sequence-Reversed Proteins.BCL::Fold--de novo prediction of complex and large protein topologies by assembly of secondary structure elementsCrystal structure of a designed, thermostable, heterotrimeric coiled coilSolution structure and dynamics of a de novo designed three-helix bundle proteinRotamer strain as a determinant of protein structural specificityRetrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteinsSynthesis and NMR solution structure of an α-helical hairpin stapled with two disulfide bridgesStructure of a protein G helix variant suggests the importance of helix propensity and helix dipole interactions in protein designTryptophan zippers: Stable, monomeric -hairpinsConversion of monomeric protein L to an obligate dimer by computational protein designThe crystal structure of indoleglycerol-phosphate synthase from Thermotoga maritima. Kinetic stabilization by salt bridgesBetaCore, a designed water soluble four-stranded antiparallel β-sheet proteinAn alanine-zipper structure determined by long range intermolecular interactionsCrystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2High-resolution design of a protein loopHIV-1 Protease Inhibitors from Inverse Design in the Substrate Envelope Exhibit Subnanomolar Binding to Drug-Resistant Variants
P2860
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P2860
De novo protein design: fully automated sequence selection
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
De novo protein design: fully automated sequence selection
@ast
De novo protein design: fully automated sequence selection
@en
De novo protein design: fully automated sequence selection
@nl
type
label
De novo protein design: fully automated sequence selection
@ast
De novo protein design: fully automated sequence selection
@en
De novo protein design: fully automated sequence selection
@nl
prefLabel
De novo protein design: fully automated sequence selection
@ast
De novo protein design: fully automated sequence selection
@en
De novo protein design: fully automated sequence selection
@nl
P3181
P1433
P1476
De novo protein design: fully automated sequence selection
@en
P2093
P3181
P356
10.1126/SCIENCE.278.5335.82
P407
P577
1997-10-03T00:00:00Z