Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
about
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG islandSirtuins: Sir2-related NAD-dependent protein deacetylasesSIRT2 as a Therapeutic Target for Age-Related DisordersMalate and fumarate extend lifespan in Caenorhabditis elegansp53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylaseNicotinamide riboside kinase structures reveal new pathways to NAD+Sir2-independent life span extension by calorie restriction in yeastpEPito: a significantly improved non-viral episomal expression vector for mammalian cellsIncreased life span due to calorie restriction in respiratory-deficient yeastRegulation of histone deacetylase 4 by binding of 14-3-3 proteinsDifferential localization of HDAC4 orchestrates muscle differentiationCloning and characterization of a histone deacetylase, HDAC9Isolation and characterization of a novel class II histone deacetylase, HDAC10JNK1 phosphorylates SIRT1 and promotes its enzymatic activityLysine glutarylation is a protein posttranslational modification regulated by SIRT5Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase familyRegulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stressSirt5 is a NAD-dependent protein lysine demalonylase and desuccinylaseHuman SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activityNampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzymeRegulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylationSirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activitySIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatinInhibition of SUV39H1 methyltransferase activity by DBC1Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteinsA high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexSide chain specificity of ADP-ribosylation by a sirtuinDeacetylation of the retinoblastoma tumour suppressor protein by SIRT1SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosisMST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylationCK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damagehSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damageSIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidationhMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cellsLife extension in Drosophila by feeding a drug.COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding proteinThe histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondriaRNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae
P2860
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P2860
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Transcriptional silencing and ...... -dependent histone deacetylase
@ast
Transcriptional silencing and ...... -dependent histone deacetylase
@en
Transcriptional silencing and ...... -dependent histone deacetylase
@nl
type
label
Transcriptional silencing and ...... -dependent histone deacetylase
@ast
Transcriptional silencing and ...... -dependent histone deacetylase
@en
Transcriptional silencing and ...... -dependent histone deacetylase
@nl
prefLabel
Transcriptional silencing and ...... -dependent histone deacetylase
@ast
Transcriptional silencing and ...... -dependent histone deacetylase
@en
Transcriptional silencing and ...... -dependent histone deacetylase
@nl
P2093
P3181
P356
P1433
P1476
Transcriptional silencing and ...... -dependent histone deacetylase
@en
P2093
C M Armstrong
L Guarente
M Kaeberlein
P2888
P304
P3181
P356
10.1038/35001622
P407
P577
2000-02-17T00:00:00Z
P5875
P6179
1019839382