Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.
about
Activating PER repressor through a DBT-directed phosphorylation switchDelayed sleep phase cases and controlsHigh-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinaseModeling of a human circadian mutation yields insights into clock regulation by PER2p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networksNEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speedGenetics of sleep and sleep disordersSetting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteinsA common polymorphism near PER1 and the timing of human behavioral rhythmsCircadian organization of behavior and physiology in DrosophilaThe transcriptional repressor DEC2 regulates sleep length in mammalsControl of sleep and wakefulnessThe period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1Drosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian functionCasein kinase 1 delta regulates the pace of the mammalian circadian clockA genome-wide RNAi screen for modifiers of the circadian clock in human cellsDifferential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)Circadian genes, rhythms and the biology of mood disordersCircadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An American Academy of Sleep Medicine reviewA small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization, and transcriptional repressor activityDrosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythmsThe period length of fibroblast circadian gene expression varies widely among human individualsPost-transcriptional control of the mammalian circadian clock: implications for health and diseaseCircadian rhythms and mood: opportunities for multi-level analyses in genomics and neuroscience: circadian rhythm dysregulation in mood disorders provides clues to the brain's organizing principles, and a touchstone for genomics and neuroscienceCircadian rhythm abnormalitiesGenetic basis of human circadian rhythm disordersMolecular architecture of the mammalian circadian clockSick and tired: how molecular regulators of human sleep schedules and duration impact immune functionControlling complexity: the clinical relevance of mouse complex geneticsDisturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant micecGMP-phosphodiesterase inhibition enhances photic responses and synchronization of the biological circadian clock in rodentsTranslational regulation of the DOUBLETIME/CKIδ/ε kinase by LARK contributes to circadian period modulationMice lacking the circadian modulators SHARP1 and SHARP2 display altered sleep and mixed state endophenotypes of psychiatric disordersGenetic Correlates of Individual Differences in Sleep Behavior of Free-Living Great Tits (Parus major).A monoclinic crystal form of casein kinase 1 δNoncanonical FK506-binding protein BDBT binds DBT to enhance its circadian function and forms foci at night.Chemical chronobiology: Toward drugs manipulating time.Life in a dark biosphere: a review of circadian physiology in "arrhythmic" environments.Manipulating the circadian and sleep cycles to protect against metabolic diseaseA PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait
P2860
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P2860
Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Functional consequences of a C ...... advanced sleep phase syndrome.
@ast
Functional consequences of a C ...... advanced sleep phase syndrome.
@en
Functional consequences of a C ...... advanced sleep phase syndrome.
@nl
type
label
Functional consequences of a C ...... advanced sleep phase syndrome.
@ast
Functional consequences of a C ...... advanced sleep phase syndrome.
@en
Functional consequences of a C ...... advanced sleep phase syndrome.
@nl
altLabel
Functional consequences of a C ...... advanced sleep phase syndrome
@en
prefLabel
Functional consequences of a C ...... advanced sleep phase syndrome.
@ast
Functional consequences of a C ...... advanced sleep phase syndrome.
@en
Functional consequences of a C ...... advanced sleep phase syndrome.
@nl
P2093
P2860
P3181
P356
P1433
P1476
Functional consequences of a C ...... advanced sleep phase syndrome.
@en
P2093
Christopher R Jones
Kazumasa Saigoh
Louis J Ptácek
Noriko Saigoh
Quasar S Padiath
Robert E Shapiro
Susan C Wu
Ying-Hui Fu
P2860
P2888
P3181
P356
10.1038/NATURE03453
P407
P50
P577
2005-03-31T00:00:00Z
P5875
P6179
1007388808