Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. - Test2 - elhamkhani - TriplyDB

Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

http://www.wikidata.org/entity/Q28142534

about

Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus From biological clock to biological rhythms.High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein Modeling of a human circadian mutation yields insights into clock regulation by PER2 Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth Rhythmic serotonin N-acetyltransferase mRNA degradation is essential for the maintenance of its circadian oscillation.The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon Biography of Joseph S. Takahashi Drosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase I Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1 Negative regulation of calcineurin signaling by Hrr25p, a yeast homolog of casein kinase I Oscillating perceptions: the ups and downs of the CLOCK protein in the mouse circadian system Drosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian function microRNA modulation of circadian-clock period and entrainment Casein kinase 1 delta regulates the pace of the mammalian circadian clock Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)A small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization, and transcriptional repressor activity Feedback repression is required for mammalian circadian clock function Drosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythms Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock A Review of Sleep and Its Disorders in Patients with Parkinson's Disease in Relation to Various Brain Structures Interdependence of nutrient metabolism and the circadian clock system: Importance for metabolic health Reciprocal Control of the Circadian Clock and Cellular Redox State - a Critical Appraisal Circadian disruption and breast cancer: an epigenetic link?Circadian genomics reveal a role for post-transcriptional regulation in mammals Diverse roles for MAPK signaling in circadian clocks ROS stress resets circadian clocks to coordinate pro-survival signals Translational regulation of the DOUBLETIME/CKIδ/ε kinase by LARK contributes to circadian period modulation Natural selection against a circadian clock gene mutation in mice.A monoclinic crystal form of casein kinase 1 δ Noncanonical FK506-binding protein BDBT binds DBT to enhance its circadian function and forms foci at night.Coordination of circadian timing in mammals Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.System-level identification of transcriptional circuits underlying mammalian circadian clocks.Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.

P2860

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P2860

Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

http://www.wikidata.org/entity/Q28142534

description

2000 nî lūn-bûn

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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2000 թվականի ապրիլին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Positional syntenic cloning an ...... mmalian circadian mutation tau

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Positional syntenic cloning an ...... mmalian circadian mutation tau

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M Menaker

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M R Ralph

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P D Zemenides

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P L Lowrey

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P2860

Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription

Molecular analysis of mammalian timeless

Identification of the mammalian homologues of the Drosophila timeless gene, Timeless1

RIGUI, a putative mammalian ortholog of the Drosophila period gene

Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family

A circadian enhancer mediates PER-dependent mRNA cycling in Drosophila melanogaster

Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2

Crystal structure of casein kinase-1, a phosphate-directed protein kinase

Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition

Light-independent role of CRY1 and CRY2 in the mammalian circadian clock.

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10775102

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circadian rhythm

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