Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.
about
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.Prp8 protein: at the heart of the spliceosomeIdentification and functional analysis of hPRP17, the human homologue of the PRP17/CDC40 yeast gene involved in splicing and cell cycle controlThe human Prp8 protein is a component of both U2- and U12-dependent spliceosomesGenetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiaeExtensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression.Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits.G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus.Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function.ATP-dependent interaction of yeast U5 snRNA loop 1 with the 5' splice site.Mutations in U5 snRNA loop 1 influence the splicing of different genes in vivo.Multiple forms of U2 snRNA coexist in the silk moth Bombyx mori.A role for the yeast cell cycle/splicing factor Cdc40 in the G1/S transition.Splicing factor slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosomeA tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast.Identification of a U2/U6 helix la mutant that influences 3' splice site selection during nuclear pre-mRNA splicing.Functional conservation of the human homolog of the yeast pre-mRNA splicing factor Prp17p.A mutation in a methionine tRNA gene suppresses the prp2-1 Ts mutation and causes a pre-mRNA splicing defect in Saccharomyces cerevisiae.U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicingFunctional roles of protein splicing factors.The function of spliceosome components in open mitosis.Yeast nuclear RNA processing.Genetic and physical interactions involving the yeast nuclear cap-binding complex.Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions.The U5 snRNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 snRNP assembly.Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly.Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae.Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing.Proximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assemblyA role for U2/U6 helix Ib in 5' splice site selection.
P2860
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P2860
Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@ast
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@en
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@nl
type
label
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@ast
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@en
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@nl
prefLabel
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@ast
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@en
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@nl
P2093
P2860
P356
P1476
Synthetic lethality of yeast s ...... th steps of pre-mRNA splicing.
@en
P2093
P2860
P304
P356
10.1128/MCB.18.4.2055
P407
P50
P577
1998-04-01T00:00:00Z