Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. - Test2 - elhamkhani - TriplyDB

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway.

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway.

http://www.wikidata.org/entity/Q27938580

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Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing.Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplication Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae Limited TTP supply affects telomere length regulation in a telomerase-independent fashion Systematic quantification of gene interactions by phenotypic array analysis The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair.Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage.Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex.Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae.POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein.The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress.The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1.Yeast Sml1, a protein inhibitor of ribonucleotide reductase.Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase.The Mck1 GSK-3 kinase inhibits the activity of Clb2-Cdk1 post-nuclear division A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiae Asf1 links Rad53 to control of chromatin assembly Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiae LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes.Yeast ribonucleotide reductase has a heterodimeric iron-radical-containing subunit.

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P2860

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway.

http://www.wikidata.org/entity/Q27938580

description

1998 nî lūn-bûn

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1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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type

label

Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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prefLabel

Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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Recovery from DNA replicationa ...... he S-phase checkpoint pathway.

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A A Alcasabas

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B A Desany

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J B Bachant

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S J Elledge

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P2860

Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes

Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

A group of interacting yeast DNA replication genes.

Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae

Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein.

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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2956-70

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10.1101/GAD.12.18.2956

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18

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12

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13540767

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9744871

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317167

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