Modulation of histone acetyltransferase activity through interaction of epstein-barr nuclear antigen 3C with prothymosin alpha
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Prothymosin alpha interacts with the CREB-binding protein and potentiates transcription.Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligaseEpstein-Barr virus nuclear antigen 3C and prothymosin alpha interact with the p300 transcriptional coactivator at the CH1 and CH3/HAT domains and cooperate in regulation of transcription and histone acetylation.Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell developmentEpstein-Barr virus nuclear antigen 3C putative repression domain mediates coactivation of the LMP1 promoter with EBNA-2.Regulation of apoptosis by the p8/prothymosin alpha complexSCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigenRole of EBNA-3 Family Proteins in EBV Associated B-cell LymphomagenesisEpigenetic Impact on EBV Associated B-Cell LymphomagenesisTat-controlled protein acetylationParathymosin affects the binding of linker histone H1 to nucleosomes and remodels chromatin structure.Prothymosin alpha associates with the oncoprotein SET and is involved in chromatin decondensation.Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migrationNovel small molecules relieve prothymosin alpha-mediated inhibition of apoptosome formation by blocking its interaction with Apaf-1.Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1.The latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus activates two major essential Epstein-Barr virus latent promotersAn Epstein-Barr virus isolated from a lymphoblastoid cell line has a 16-kilobase-pair deletion which includes gp350 and the Epstein-Barr virus nuclear antigen 3ALatency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus interacts with Tat and activates the long terminal repeat of human immunodeficiency virus type 1 in human cells.Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical.Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1The metastatic suppressor Nm23-H1 interacts with EBNA3C at sequences located between the glutamine- and proline-rich domains and can cooperate in activation of transcriptionThe importance of epigenetic alterations in the development of epstein-barr virus-related lymphomas.Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression.EBNA3C coactivation with EBNA2 requires a SUMO homology domain.Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines.Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities.Epstein-Barr Virus Proteins EBNA3A and EBNA3C Together Induce Expression of the Oncogenic MicroRNA Cluster miR-221/miR-222 and Ablate Expression of Its Target p57KIP2.EBV Nuclear Antigen 3C Mediates Regulation of E2F6 to Inhibit E2F1 Transcription and Promote Cell Proliferation.Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growthEBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexesProthymosin α overexpression contributes to the development of pulmonary emphysema.Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth.Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation.Viral manipulation of the host epigenome for oncogenic transformation.Epstein-Barr virus nuclear protein 3C domains necessary for lymphoblastoid cell growth: interaction with RBP-Jkappa regulates TCL1.Impact of EBV essential nuclear protein EBNA-3C on B-cell proliferation and apoptosis.Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis.EBNA-3B- and EBNA-3C-regulated cellular genes in Epstein-Barr virus-immortalized lymphoblastoid cell lines.Deregulation of the cell cycle machinery by Epstein-Barr virus nuclear antigen 3C.Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases.
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P2860
Modulation of histone acetyltransferase activity through interaction of epstein-barr nuclear antigen 3C with prothymosin alpha
description
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im August 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/08/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/08/01)
@nl
наукова стаття, опублікована в серпні 2000
@uk
مقالة علمية (نشرت في أغسطس 2000)
@ar
name
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@ast
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@en
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@nl
type
label
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@ast
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@en
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@nl
prefLabel
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@ast
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@en
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@nl
P2860
P3181
P1476
Modulation of histone acetyltr ...... igen 3C with prothymosin alpha
@en
P2093
E. S. Robertson
M. A. Cotter
P2860
P304
P3181
P356
10.1128/MCB.20.15.5722-5735.2000
P407
P577
2000-08-01T00:00:00Z