HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator
about
The Vpr protein from HIV-1: distinct roles along the viral life cycleHuman immunodeficiency virus type 1 Vpr-dependent cell cycle arrest through a mitogen-activated protein kinase signal transduction pathwayEpstein-Barr virus nuclear antigen 3C and prothymosin alpha interact with the p300 transcriptional coactivator at the CH1 and CH3/HAT domains and cooperate in regulation of transcription and histone acetylation.Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell developmentVisualizing Vpr-induced G2 arrest and apoptosisModulation of histone acetyltransferase activity through interaction of epstein-barr nuclear antigen 3C with prothymosin alphaSynthesis of a Vpr-Binding Derivative for Use as a Novel HIV-1 InhibitorRegulation of cardiomyocyte hypertrophy in diabetes at the transcriptional levelHuman immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA.Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus.Pathogenesis of HIV-1 infection within bone marrow cells.Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case.HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1.Functional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.Activation of transcription factors NF-kappaB and NF-IL-6 by human immunodeficiency virus type 1 protein R (Vpr) induces interleukin-8 expressionGenetic variation and HIV-associated neurologic disease.A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)Vpr-host interactions during HIV-1 viral life cycle.Protein kinase A phosphorylation activates Vpr-induced cell cycle arrest during human immunodeficiency virus type 1 infection.Exposed hydrophobic residues in human immunodeficiency virus type 1 Vpr helix-1 are important for cell cycle arrest and cell deathNuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex.Modulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates.Strategies in subversion: de-regulation of the mammalian cell cycle by viral gene products.Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor.Human immunodeficiency virus type 1 (HIV-1) Vpr enhances expression from unintegrated HIV-1 DNA.HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic interventionSET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress.HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure researchCAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibitionEpigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation.HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages.Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins.The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor.Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cellsHIV Vpr protein upregulates microRNA-122 expression and stimulates hepatitis C virus replicationHuman immunodeficiency virus viral protein R as an extracellular protein in neuropathogenesis.The human immunodeficiency virus type 1 Vpr protein and its carboxy-terminally truncated form induce apoptosis in tumor cells.An HIV-1 replication pathway utilizing reverse transcription products that fail to integrate.
P2860
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P2860
HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
HIV transcriptional activation ...... iated by the p300 co-activator
@ast
HIV transcriptional activation ...... iated by the p300 co-activator
@en
HIV transcriptional activation ...... iated by the p300 co-activator
@nl
type
label
HIV transcriptional activation ...... iated by the p300 co-activator
@ast
HIV transcriptional activation ...... iated by the p300 co-activator
@en
HIV transcriptional activation ...... iated by the p300 co-activator
@nl
prefLabel
HIV transcriptional activation ...... iated by the p300 co-activator
@ast
HIV transcriptional activation ...... iated by the p300 co-activator
@en
HIV transcriptional activation ...... iated by the p300 co-activator
@nl
P2093
P2860
P356
P1476
HIV transcriptional activation ...... iated by the p300 co-activator
@en
P2093
C Woffendin
L K Felzien
R A Subbramanian
P2860
P304
P356
10.1073/PNAS.95.9.5281
P407
P577
1998-04-01T00:00:00Z