Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
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Dual role of macrophage migration inhibitory factor (MIF) in human breast cancerCSN controls NF-kappaB by deubiquitinylation of IkappaBalphaThe subunit CSN6 of the COP9 signalosome is cleaved during apoptosisC10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancerInteraction and colocalization of PGP9.5 with JAB1 and p27(Kip1)A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3Aurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinaseRIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteinsJab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradationDynamic regulation of the COP9 signalosome in response to DNA damageIsolation and characterization of cytoplasmic cyclin D1 mutants14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradationRole of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrestCRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisNovel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functionsCOP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin systemAnalysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulationCharacterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complexProtein kinase CK2 and protein kinase D are associated with the COP9 signalosomeLigand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteinsShuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationSpy1 interacts with p27Kip1 to allow G1/S progressionEpstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5Role of the F-box protein Skp2 in adhesion-dependent cell cycle progressionA single-nucleotide polymorphism in the human p27kip1 gene (-838C>A) affects basal promoter activity and the risk of myocardial infarctionThe functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibitionThe F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8pS100A7 (psoriasin) expression is associated with aggressive features and alteration of Jab1 in ductal carcinoma in situ of the breastThe Relevance of Women's Diseases, Jun Activation-domain Binding Protein 1 (JAB1) and p27(kip1)The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyNuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4.Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae.New insights on Schwann cell developmentERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development
P2860
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P2860
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@ast
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@en
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@nl
type
label
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@ast
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@en
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@nl
prefLabel
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@ast
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@en
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@nl
P2093
P3181
P356
P1433
P1476
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
@en
P2093
P2888
P3181
P356
10.1038/18230
P407
P577
1999-03-11T00:00:00Z
P6179
1025768697