PERK mediates cell-cycle exit during the mammalian unfolded protein response
about
ERp29 induces breast cancer cell growth arrest and survival through modulation of activation of p38 and upregulation of ER stress protein p58IPKPolycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alphaTranslational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient StressDistinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein responseRegulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.The roles of nitric oxide synthase and eIF2alpha kinases in regulation of cell cycle upon UVB-irradiationNrf2 is a direct PERK substrate and effector of PERK-dependent cell survivalThe loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesisRheumatoid arthritis as a hyper-endoplasmic-reticulum-associated degradation diseaseMechanisms of benzene-induced hematotoxicity and leukemogenicity: cDNA microarray analyses using mouse bone marrow tissue.The Canine Papillomavirus E5 Protein Signals from the Endoplasmic ReticulumDcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiaeThe Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum StressMechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone RemodelingTumor progression and the different faces of the PERK kinaseThe protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domainPERK Integrates Oncogenic Signaling and Cell Survival During Cancer DevelopmentMechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signallingUPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levelsDeletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stressPERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiationActivating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress responseWFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cellsTranslation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent mannerPERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathwayS-glutathionylation: from molecular mechanisms to health outcomesThe anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress.Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation.Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound.Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesisNew Insights into the Pathogenesis of Alcohol-Induced ER Stress and Liver DiseasesThe anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells.Resveratrol-induced cytotoxicity in human Burkitt's lymphoma cells is coupled to the unfolded protein response.Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response.Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein.Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cellsPlasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response.Stress signaling and the shaping of the mammary tissue in development and cancer.Riboflavin deficiency impairs oxidative folding and secretion of apolipoprotein B-100 in HepG2 cells, triggering stress response systems.PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
P2860
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P2860
PERK mediates cell-cycle exit during the mammalian unfolded protein response
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@ast
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@en
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@nl
type
label
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@ast
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@en
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@nl
prefLabel
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@ast
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@en
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@nl
P2860
P3181
P356
P1476
PERK mediates cell-cycle exit during the mammalian unfolded protein response
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.220247197
P407
P577
2000-11-07T00:00:00Z