The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42
about
Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex.Calmodulin-kinases: modulators of neuronal development and plasticityp120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherinsThe neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cellsThe nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activityThe dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patternsKCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX.Non-muscle myosin II regulates neuronal actin dynamics by interacting with guanine nucleotide exchange factorsCrystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerizationActin-Dependent Alterations of Dendritic Spine Morphology in ShankopathiesShank2 associates with and regulates Na+/H+ exchanger 3A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotypeSmaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapsesShank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanismMolecular handoffs in nitrergic neurotransmissionRhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development.Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism.Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalitiesUncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spinesTranscriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptideGIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion.Shank2 redistributes with NaPilla during regulated endocytosisControl of synapse development and plasticity by Rho GTPase regulatory proteins.Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform.Affinity Enhancement by Ligand Clustering Effect Inspired by Peptide Dendrimers-Shank PDZ Proteins Interactions.The molecular genetics of autism spectrum disorders: genomic mechanisms, neuroimmunopathology, and clinical implicationsMice lacking the PSD-95-interacting E3 ligase, Dorfin/Rnf19a, display reduced adult neurogenesis, enhanced long-term potentiation, and impaired contextual fear conditioningAlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling.A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function.The PIX-GIT complex: a G protein signaling cassette in control of cell shapeDestabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticityShank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapsesRegulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.Synaptic Actin Dysregulation, a Convergent Mechanism of Mental Disorders?Synaptic plasticity, a symphony in GEF.Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures.
P2860
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P2860
The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@ast
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@en
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@nl
type
label
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@ast
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@en
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@nl
prefLabel
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@ast
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@en
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@nl
P2093
P2860
P3181
P356
P1476
The Shank family of postsynapt ...... ange factor for Rac1 and Cdc42
@en
P2093
Dongeun Park
Eunhye Park
Eunjoon Kim
Jae-Ran Lee
Jeonghoon Choi
Jiyoung Yoon
Moonseok Na
P2860
P304
P3181
P356
10.1074/JBC.M301052200
P407
P50
P577
2003-05-23T00:00:00Z