Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
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IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradationThe E3 ligase Smurf1 regulates Wolfram syndrome protein stability at the endoplasmic reticulumRegulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite developmentCKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradationSCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundanceBinding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activityPost-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasionREGgamma proteasome mediates degradation of the ubiquitin ligase Smurf1HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradationOverexpression of CD99 Increases the Migration and Invasiveness of Human Malignant Glioma CellsIncreased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancerTRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaBMicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoAUbiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarityGTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoThe Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cellsCell polarity signaling in the plasticity of cancer cell invasivenessHomeostatic Signaling by Cell-Cell Junctions and Its Dysregulation during Cancer ProgressionKey role for ubiquitin protein modification in TGFβ signal transductionCerebral cavernous malformation is a vascular disease associated with activated RhoA signalingRho GTPase regulation by miRNAs and covalent modificationsRho GTPases in collective cell migrationCompetition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin ContractilityA lateral signalling pathway coordinates shape volatility during cell migration.Rac activation by the T-cell receptor inhibits T cell migrationThe Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms.A decade of the anaphase-promoting complex in the nervous systemSignaling via the Tgf-beta type I receptor Alk5 in heart developmentUbiquitination of RhoA by Smurf1 promotes neurite outgrowthSmurf1 directly targets hPEM-2, a GEF for Cdc42, via a novel combination of protein interaction modules in the ubiquitin-proteasome pathwayTargeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cellsThe Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization.Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradationProtein kinase Czeta and glycogen synthase kinase-3beta control neuronal polarity in developing rodent enteric neurons, whereas SMAD specific E3 ubiquitin protein ligase 1 promotes neurite growth but does not influence polarityAutophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.Non-Smad pathways in TGF-beta signalingSystematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts.
P2860
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P2860
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@ast
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@en
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@nl
type
label
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@ast
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@en
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@nl
prefLabel
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@ast
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@en
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@nl
P2093
P3181
P356
P1433
P1476
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
@en
P2093
Abiodun A Ogunjimi
Barish Ozdamar
Evguenia Alexandrova
Gerald H Thomsen
Hong-Rui Wang
Jeffrey L Wrana
P304
P3181
P356
10.1126/SCIENCE.1090772
P407
P577
2003-12-05T00:00:00Z