Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells
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SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundancePin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteinsSmurf2 participates in human trophoblast cell invasion by inhibiting TGF-beta type I receptorTranscription alterations of members of the ubiquitin-proteasome network in prostate carcinoma.Roles of E3 ubiquitin ligases in cell adhesion and migration.The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation.Suppression of p53 activity through the cooperative action of Ski and histone deacetylase SIRT1.The E3 ubiquitin ligase SMAD ubiquitination regulatory factor 2 negatively regulates Krüppel-like factor 5 protein.Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20.Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligaseThe ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis.Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma.The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial-mesenchymal transition in a sumoylation-regulated manner.Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signalingSmurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesisRegulation of endothelial barrier function by TGF-β type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90.SMURF1 plays a role in EGF-induced breast cancer cell migration and invasion.Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis.Smurf control in bone cells.SMURF and NEDD4: sharp shooters monitor the gate keepers and ion traffic controllers of lead astray cell.Ubiquitination: Added complexity in Ras and Rho family GTPase function.A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.Crosstalk between kinases and Nedd4 family ubiquitin ligases.Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1.Regulation of early xenopus embryogenesis by Smad ubiquitination regulatory factor 2.E3 ubiquitin ligases in cancer and implications for therapies.Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome SystemSmurfs in Protein Homeostasis, Signaling, and Cancer
P2860
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P2860
Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@ast
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@en
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@nl
type
label
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@ast
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@en
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@nl
prefLabel
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@ast
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@en
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@nl
P2093
P2860
P356
P1476
Smurf2 induces ubiquitin-depen ...... gration of breast cancer cells
@en
P2093
Daizo Koinuma
Erina Fukunaga
Kana Horiguchi
Kouichiro Goto
Masao Saitoh
Setsuro Komiya
Takeshi Imamura
Yasumichi Inoue
P2860
P304
35660-35667
P356
10.1074/JBC.M710496200
P407
P50
P577
2008-10-16T00:00:00Z