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ZBP1 recognition of beta-actin zipcode induces RNA loopingThe Enzyme Function Initiative.Protein production and purificationStructure-based activity prediction for an enzyme of unknown functionDiscovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screeningVisualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprintingX-ray crystallography over the past decade for novel drug discovery - where are we heading next?Better and faster: improvements and optimization for mammalian recombinant protein productionRecent advances in mammalian protein productionPlasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal modelHow H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discriminationStructural genomics: A pipeline for providing structures for the biologistPolylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolutionClosed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migrationStructure of mutant human carbonmonoxyhemoglobin C (betaE6K) at 2.0 A resolutionCrystal structure of PTP1B complexed with a potent and selective bidentate inhibitorCrystal structure of the receptor-binding domain of human B7-2: Insights into organization and signalingInhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues †Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitorPicomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-AMechanistic diversity in the RuBisCO superfamily: the "enolase" in the methionine salvage pathway in Geobacillus kaustophilusT cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surfaceNeighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †Structure of CD84 provides insight into SLAM family functionStructural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylasePrediction and assignment of function for a divergent N-succinyl amino acid racemaseEvolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibitionEvolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivoransAssembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for functionStructural genomics of protein phosphatasesStructural basis for the coevolution of a viral RNA–protein complexl -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside PhosphorylaseEvolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamilyStructure of Ca 2+ -Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA †Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2Structural Basis for Substrate Specificity in Phosphate Binding (β/α) 8 -Barrels: d -Allulose 6-Phosphate 3-Epimerase from Escherichia coli K-12 † ‡Structure of Diethyl Phosphate Bound to the Binuclear Metal Center of Phosphotriesterase † ‡Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine modelsEvolution of Enzymatic Activities in the Enolase Superfamily: l -Rhamnonate Dehydratase † ‡
P50
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P50
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