The TIM-barrel fold: a versatile framework for efficient enzymes
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Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution.GH97 is a new family of glycoside hydrolases, which is related to the alpha-galactosidase superfamily.CLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activityFunctional evolution of two subtly different (similar) foldsCrystal structure ofBacillus subtilis ioli shows endonuclase IV fold with altered Zn bindingCrystal structure ofEscherichia coli EC1530, a glyoxylate induced protein YgbMBiochemical and structural studies of malate synthase from Mycobacterium tuberculosisDeep trefoil knot implicated in RNA binding found in an archaebacterial proteinFunction, Structure, and Evolution of the RubisCO-Like Proteins and Their RubisCO HomologsStructure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel FoldMolecular Mechanisms of Yeast Cell Wall Glucan RemodelingStructural Characterization of the Molecular Events during a Slow Substrate–Product Transition in Orotidine 5′-Monophosphate DecarboxylaseEstablishing wild-type levels of catalytic activity on natural and artificial ( )8-barrel protein scaffoldsStructure of a Class I Tagatose-1,6-bisphosphate AldolaseCrystal Structure of Histamine Dehydrogenase from Nocardioides simplexProbing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stabilityCrystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroateStructure of the signal transduction protein TRAP (target of RNAIII-activating protein)Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound ComplexesStructures of Phytophthora RXLR Effector Proteins: A CONSERVED BUT ADAPTABLE FOLD UNDERPINS FUNCTIONAL DIVERSITYAn octamer of enolase from Streptococcus suisExploring Symmetry as an Avenue to the Computational Design of Large Protein DomainsStructure and activity of exo-1,3/1,4-β-glucanase from marine bacterium Pseudoalteromonas sp. BB1 showing a novel C-terminal domainA monomeric TIM-barrel structure from Pyrococcus furiosus is optimized for extreme temperaturesA sugar isomerization reaction established on various (βα)₈-barrel scaffolds is based on substrate-assisted catalysisEnzyme Architecture: The Effect of Replacement and Deletion Mutations of Loop 6 on Catalysis by Triosephosphate IsomeraseEstablishing catalytic activity on an artificial (βα)8-barrel protein designed from identical half-barrelsInsights into the bioactivity of mensacarcin and epoxide formation by MsnO8Structural insights into N-terminal to C-terminal interactions and implications for thermostability of a (β/α)8-triosephosphate isomerase barrel enzymeStructural and functional analysis of SleL, a peptidoglycan lysin involved in germination of Bacillus sporesProbing the role of highly conserved residues in triosephosphate isomerase--analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzymeReversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteinsThe phospholipase C isozymes and their regulationRelaxed specificity in aromatic prenyltransferasesDe novo enzyme design using Rosetta3Alternative splice variants in TIM barrel proteins from human genome correlate with the structural and evolutionary modularity of this versatile protein foldOctarellin VI: using rosetta to design a putative artificial (β/α)8 proteinInferring meaningful communities from topology-constrained correlation networksThe enzymatic and metabolic capabilities of early lifeA Molecular Dynamics Study on Controlling the Self-Assembly of β-Sheet Peptides with Designer Nanorings.
P2860
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P2860
The TIM-barrel fold: a versatile framework for efficient enzymes
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2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
@yue
2001年論文
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2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
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name
The TIM-barrel fold: a versatile framework for efficient enzymes
@ast
The TIM-barrel fold: a versatile framework for efficient enzymes
@en
The TIM-barrel fold: a versatile framework for efficient enzymes
@nl
type
label
The TIM-barrel fold: a versatile framework for efficient enzymes
@ast
The TIM-barrel fold: a versatile framework for efficient enzymes
@en
The TIM-barrel fold: a versatile framework for efficient enzymes
@nl
prefLabel
The TIM-barrel fold: a versatile framework for efficient enzymes
@ast
The TIM-barrel fold: a versatile framework for efficient enzymes
@en
The TIM-barrel fold: a versatile framework for efficient enzymes
@nl
P2860
P3181
P1433
P1476
The TIM-barrel fold: a versatile framework for efficient enzymes
@en
P2093
R K Wierenga
P2860
P3181
P356
10.1016/S0014-5793(01)02236-0
P407
P577
2001-03-16T00:00:00Z