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Delayed and accelerated aging share common longevity assurance mechanismsOverexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instabilityThe nuclear envelopathies and human diseasesControlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitinEvolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in miceGrowth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASGTAp63 prevents premature aging by promoting adult stem cell maintenanceModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesSIRT6 in DNA repair, metabolism and ageingDeletion of Ku70, Ku80, or both causes early aging without substantially increased cancerA transcriptional profile of aging in the human kidneyL2L: a simple tool for discovering the hidden significance in microarray expression dataAcute systemic DNA damage in youth does not impair immune defense with agingDNA Damage: A Main Determinant of Vascular AgingRole of Myofibrillar Protein Catabolism in Development of Glucocorticoid Myopathy: Aging and Functional Activity AspectsMolecular mechanisms of biological aging in intervertebral discsAre Anxiety Disorders Associated with Accelerated Aging? A Focus on NeuroprogressionThe short-lived African turquoise killifish: an emerging experimental model for ageingDNA repair and aging: the impact of the p53 familyMitochondrial adaptations evoked with exercise are associated with a reduction in age-induced testicular atrophy in Fischer-344 ratsAn overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial jointsSomatic mutations in aging, cancer and neurodegenerationMolecular mechanism of extrinsic factors affecting anti-aging of stem cellsAdaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in miceReduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutationLaminopathies and the long strange trip from basic cell biology to therapy'Accelerated aging': a primrose path to insight?Accelerating aging by mouse reverse genetics: a rational approach to understanding longevityRebuttal to Miller: 'Accelerated aging': a primrose path to insight?'Genomic instability in laminopathy-based premature agingDeletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell lossDNA damage response genes and the development of cancer metastasisReduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- miceTelomere shortening exposes functions for the mouse Werner and Bloom syndrome genesDNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouseMisregulation of poly(ADP-ribose) polymerase-1 activity and cell type-specific loss of poly(ADP-ribose) synthesis in the cerebellum of aged ratsRetinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndromep63 deficiency activates a program of cellular senescence and leads to accelerated agingCisd2 deficiency drives premature aging and causes mitochondria-mediated defects in miceThe ERCC6 gene and age-related macular degeneration
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Aging and genome maintenance: lessons from the mouse?
@ast
Aging and genome maintenance: lessons from the mouse?
@en
Aging and genome maintenance: lessons from the mouse?
@nl
type
label
Aging and genome maintenance: lessons from the mouse?
@ast
Aging and genome maintenance: lessons from the mouse?
@en
Aging and genome maintenance: lessons from the mouse?
@nl
prefLabel
Aging and genome maintenance: lessons from the mouse?
@ast
Aging and genome maintenance: lessons from the mouse?
@en
Aging and genome maintenance: lessons from the mouse?
@nl
P2093
P3181
P356
P1433
P1476
Aging and genome maintenance: lessons from the mouse?
@en
P2093
Harry van Steeg
Jan Hoeijmakers
Judith Campisi
Paul Hasty
P304
P3181
P356
10.1126/SCIENCE.1079161
P407
P577
2003-02-28T00:00:00Z