The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
about
Deubiquitylating enzymes and diseaseGenome-wide linkage and association analyses implicate FASN in predisposition to Uterine LeiomyomataThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2Suppression of cancer cell growth by promoting cyclin D1 degradationMdmX is a substrate for the deubiquitinating enzyme USP2aO-GlcNAcylation and the Metabolic Shift in High-Proliferating Cells: All the Evidence Suggests that Sugars Dictate the Flux of Lipid Biogenesis in Tumor ProcessesThe potential of ¹¹C-acetate PET for monitoring the Fatty acid synthesis pathway in TumorsLipid metabolism in prostate cancerUSP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational LevelA synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2De novo fatty acid biosynthesis contributes significantly to establishment of a bioenergetically favorable environment for vaccinia virus infectionBlockade of fatty acid synthase triggers significant apoptosis in mantle cell lymphomaRegulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity.Screen for ISG15-crossreactive deubiquitinases.Hepatocyte RXRalpha deficiency in matured and aged mice: impact on the expression of cancer-related hepatic genes in a gender-specific mannerFatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer.Fatty acid synthase reprograms the epigenome in uterine leiomyosarcomas.Ubiquitin-specific cysteine protease 2a (USP2a) regulates the stability of Aurora-A.The de-ubiquitinylating enzyme, USP2, is associated with the circadian clockwork and regulates its sensitivity to light.Biochemistry, molecular biology, and pharmacology of fatty acid synthase, an emerging therapeutic target and diagnosis/prognosis marker.HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase.Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2.The pathogenesis of prostate cancer: from molecular to metabolic alterations.Molecular pathways and targets in prostate cancerABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53.Midkine, a heparin-binding protein, is increased in the diabetic mouse kidney postmenopause.Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.Discovery of putative oocyte quality markers by comparative ExacTag proteomicsIncreased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats.Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme.Reduced association of anti-apoptotic protein Mcl-1 with E3 ligase Mule increases the stability of Mcl-1 in breast cancer cells.Screening of DUB activity and specificity by MALDI-TOF mass spectrometryCancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.Roles of ubiquitination and SUMOylation on prostate cancer: mechanisms and clinical implications.Metabolic alterations and targeted therapies in prostate cancer.Fatty acid synthase as a potential therapeutic target in cancer.Ubiquitin-specific protease 2 regulates hepatic gluconeogenesis and diurnal glucose metabolism through 11β-hydroxysteroid dehydrogenase 1The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer.Complementary Cholesterol-Lowering Response of a Phytosterol/α-Lipoic Acid Combination in Obese Zucker Rats.
P2860
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P2860
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@ast
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@en
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@nl
type
label
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@ast
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@en
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@nl
prefLabel
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@ast
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@en
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@nl
P2093
P3181
P1433
P1476
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
@en
P2093
Antonella Baron
Dieter Huesken
Edgard Graner
Johann Zimmermann
Lisa J Weinstein
Mirna Lechpammer
Sabina Signoretti
Sabrina Rossi
Toshiro Migita
P304
P3181
P356
10.1016/S1535-6108(04)00055-8
P407
P50
P577
2004-03-01T00:00:00Z