Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
about
Ubc13: the Lys63 ubiquitin chain building machinePoly-ubiquitination in TNFR1-mediated necroptosisSubstrate specificity of the ubiquitin and Ubl proteasesRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINOptimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblottingK63 polyubiquitination is a new modulator of the oxidative stress responseDeubiquitinases: Novel Therapeutic Targets in Immune Surveillance?Linear ubiquitination in immunityThe deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosisUSP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responsesCYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune SignalingA Wolbachia deubiquitylating enzyme induces cytoplasmic incompatibilityLithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2aTargeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.Assembly and specific recognition of k29- and k33-linked polyubiquitin.Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitinSculpting the proteome with small moleculesThe human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerizationComparison of native and non-native ubiquitin oligomers reveals analogous structures and reactivities.Quantitative MALDI-MS Binding Assays: An Alternative to Radiolabeling.SPRi-MALDI MS: characterization and identification of a kinase from cell lysate by specific interaction with different designed ankyrin repeat proteins.Ubiquitin-Specific Proteases as Druggable Targets.Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake.The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cellsDeubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease.Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death.Specificity and disease in the ubiquitin systemSPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice.LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.Chemical ubiquitination for decrypting a cellular code.The emerging role of deubiquitination in nucleotide excision repair.Activity-based probes for the ubiquitin conjugation-deconjugation machinery: new chemistries, new tools, and new insights.CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different.Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC SignalingCell Lysate-Based AlphaLISA Deubiquitinase Assay Platform for Identification of Small Molecule Inhibitors.Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets.
P2860
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P2860
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@ast
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@en
type
label
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@ast
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@en
prefLabel
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@ast
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@en
P2093
P2860
P50
P356
P1476
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
@en
P2093
Ana B Perez-Oliva
Axel Knebel
Melanie Wightman
Nathanael S Gray
Nicholas A Morrice
Richard Ewan
Sara J Buhrlage
P2860
P2888
P356
10.1038/NCOMMS5763
P407
P577
2014-08-27T00:00:00Z