The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma - Test2 - elhamkhani - TriplyDB

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

http://www.wikidata.org/entity/Q28255650

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Shepherding AKT and androgen receptor by Ack1 tyrosine kinase Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1 Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome Tumor suppressor and hepatocellular carcinoma A novel approach to simultaneously scan genes at fragile sites 17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.Wwox-Brca1 interaction: role in DNA repair pathway choice Fhit loss in lung preneoplasia: relation to DNA damage response checkpoint activation.Molecular alterations in the tumor suppressor gene WWOX in oral leukoplakias.WWOX hypomorphic mice display a higher incidence of B-cell lymphomas and develop testicular atrophy.Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status Association between decreased WWOX protein expression and thyroid cancer development WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.Oncosuppressor proteins of fragile sites are reduced in cervical cancer.Molecular analysis of WWOX expression correlation with proliferation and apoptosis in glioblastoma multiforme Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species.Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression.Common chromosome fragile sites in human and murine epithelial cells and FHIT/FRA3B loss-induced global genome instability The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding FHIT gene expression is repressed by mitogenic signaling through the PI3K/AKT/FOXO pathway.Response of subtype-specific human breast cancer-derived cells to poly(ADP-ribose) polymerase and checkpoint kinase 1 inhibition.Expression of WW domain-containing oxidoreductase WWOX in pterygium Aberrant crypt focus and fragile histidine triad protein in sporadic colorectal carcinoma.Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas.WWOX in biological control and tumorigenesis.Aberrant expression of DNA damage response proteins is associated with breast cancer subtype and clinical features The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX.Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical features Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment.Nit1 and Fhit tumor suppressor activities are additive.Fhit loss-associated initiation and progression of neoplasia in vitro.WWOX gene and gene product: tumor suppression through specific protein interactions.WW domain-containing oxidoreductase's role in myriad cancers: clinical significance and future implications.Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and Tumors The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.

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P2860

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

http://www.wikidata.org/entity/Q28255650

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2004 nî lūn-bûn

@nan

2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@ast

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@en

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@nl

type

label

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@ast

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@en

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@nl

prefLabel

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@ast

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@en

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

@nl

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The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

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P2093

Aysegul Uner

http://www.w3.org/2001/XMLSchema#string

Dimitrios Iliopoulos

http://www.w3.org/2001/XMLSchema#string

Gulnur Guler

http://www.w3.org/2001/XMLSchema#string

Kay Huebner

http://www.w3.org/2001/XMLSchema#string

Nilufer Guler

http://www.w3.org/2001/XMLSchema#string

Peter McCue

http://www.w3.org/2001/XMLSchema#string

Shuang-Yin Han

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Walter W Hauck

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1605-14

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scholarly article

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4000953

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10.1002/CNCR.20137

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8

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100

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2004-04-15T00:00:00Z

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8627671

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15073846

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