DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ - Test2 - elhamkhani - TriplyDB

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

http://www.wikidata.org/entity/Q28263318

about

DNA polymerase delta in DNA replication and genome maintenance Eukaryotic DNA polymerase ζ Emerging critical roles of Fe-S clusters in DNA replication and repair.Def1 promotes the degradation of Pol3 for polymerase exchange to occur during DNA-damage--induced mutagenesis in Saccharomyces cerevisiae.A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiae DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε.The C-terminal domain of the DNA polymerase catalytic subunit regulates the primase and polymerase activities of the human DNA polymerase α-primase complex Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage.Translesion DNA polymerases The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability Rescue from replication stress during mitosis.The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ.REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ Crystal structure of the human primase FF483-484 motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance Essential role of the iron-sulfur cluster binding domain of the primase regulatory subunit Pri2 in DNA replication initiation.Loss of Pol32 in Drosophila melanogaster causes chromosome instability and suppresses variegation.Exo1 phosphorylation status controls the hydroxyurea sensitivity of cells lacking the Pol32 subunit of DNA polymerases delta and zeta Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit.The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability.Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.Subunit sharing among high- and low-fidelity DNA polymerases.A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis Insight into the Human DNA Primase Interaction with Template-Primer.PCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activities.Replicative DNA polymerases.Proficient Replication of the Yeast Genome by a Viral DNA Polymerase Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.Fate of the replisome following arrest by UV-induced DNA damage in Escherichia coli DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on Rev1 but not Polη.Reconstitution of a eukaryotic replisome reveals the mechanism of asymmetric distribution of DNA polymerases The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis.DNA damage tolerance and a web of connections with DNA repair at Yale.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass.Breakthrough for a DNA break-preventer.Elaborated Action of the Human Primosome.Regulation of human DNA polymerase delta in the cellular responses to DNA damage.

P2860

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P2860

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

http://www.wikidata.org/entity/Q28263318

description

2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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name

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

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DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

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DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

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type

label

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@ast

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@en

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@nl

prefLabel

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@ast

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@en

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@nl

P1433

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JBC.M112.351122

P1433

Journal of Biological Chemistry

P1476

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

@en

P2093

Andrey G Baranovskiy

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Artem G Lada

http://www.w3.org/2001/XMLSchema#string

Hollie M Siebler

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Tahir H Tahirov

http://www.w3.org/2001/XMLSchema#string

Yinbo Zhang

http://www.w3.org/2001/XMLSchema#string

Youri I Pavlov

http://www.w3.org/2001/XMLSchema#string

P2860

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol.

Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1

Functional roles of p12, the fourth subunit of human DNA polymerase delta

X-ray structure of the complex of regulatory subunits of human DNA polymerase delta

3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases

Protein structure prediction on the Web: a case study using the Phyre server

The DNA repair helicases XPD and FancJ have essential iron-sulfur domains.

Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.

The C-terminal zinc finger of the catalytic subunit of DNA polymerase delta is responsible for direct interaction with the B-subunit.

A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

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17281-7

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scholarly article

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1614731

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P356

10.1074/JBC.M112.351122

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P433

21

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P478

287

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P577

2012-05-18T00:00:00Z

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P5875

223978898

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P698

22465957

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P921

DNA polymerase alpha 1, catalytic subunit

REV3 like, DNA directed polymerase zeta catalytic subunit

DNA polymerase epsilon 2, accessory subunit

DNA polymerase delta 1, catalytic subunit

DNA polymerase delta 2, accessory subunit

DNA polymerase epsilon, catalytic subunit

DNA polymerase alpha 2, accessory subunit

DNA polymerase delta 3, accessory subunit

P932

3366816

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