The CHEK2 gene and inherited breast cancer susceptibility - Test2 - elhamkhani - TriplyDB

The CHEK2 gene and inherited breast cancer susceptibility

The CHEK2 gene and inherited breast cancer susceptibility

http://www.wikidata.org/entity/Q28265315

about

Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals Trial watch - inhibiting PARP enzymes for anticancer therapy Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy Targeting ATM-deficient CLL through interference with DNA repair pathways The convergence of DNA damage checkpoint pathways and androgen receptor signaling in prostate cancer Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway Update on Poly-ADP-ribose polymerase inhibition for ovarian cancer treatment Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study ATM Signaling Pathway Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study.Hereditary breast cancer: ever more pieces to the polygenic puzzle.Germline mutations and polymorphisms in the origins of cancers in women.A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data An association study between CHEK2 gene mutations and susceptibility to breast cancer.Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2.Identification of Novel Susceptibility Genes for Breast Cancer - Genome-Wide Association Studies or Evaluation of Candidate Genes?Survival and contralateral breast cancer in CHEK2 1100delC breast cancer patients: impact of adjuvant chemotherapy.Breast cancer susceptibility: current knowledge and implications for genetic counselling The checkpointkinase 2 (CHK2) 1100delC germ line mutation is not associated with the development of squamous cell carcinoma of the head and neck (SCCHN).Genotoxic exposure during juvenile growth of mammary gland depletes stem cell activity and inhibits Wnt signaling.Genomic rearrangements in BRCA1 and BRCA2: A literature review.ATM and breast cancer susceptibility.Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling.Low prevalence of CHEK2 gene mutations in multiethnic cohorts of breast cancer patients in Malaysia.A multistage association study identifies a breast cancer genetic locus at NCOA7.Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.Sensitivity to systemic therapy for metastatic breast cancer in CHEK2 1100delC mutation carriers Response to DNA damage of CHEK2 missense mutations in familial breast cancer.MinePath: Mining for Phenotype Differential Sub-paths in Molecular Pathways.Distinct DNA damage determines differential phosphorylation of Chk2.Rapid Detection Method for the Four Most Common CHEK2 Mutations Based on Melting Profile Analysis A population-based study of DNA repair gene variants in relation to non-melanoma skin cancer as a marker of a cancer-prone phenotype CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer.Clinical relevance of CHEK2 and NBN mutations in the macedonian population Therapeutic potential of stem cells expressing suicide genes that selectively target human breast cancer cells: evidence that they exert tumoricidal effects via tumor tropism (review).Hereditary breast cancer in the Han Chinese population.

P2860

Q22000758-4D717487-2D5B-4C19-978C-1E5EB318C088 Q26745673-64CCE06C-22E3-4847-AA33-38D26518BEC5 Q26745686-3E889D58-69D1-4F62-A11A-CAAA001AFAE7 Q26822592-0962A07B-93F7-4C84-BE04-69D8E01C194A Q27014101-654F2262-DF5E-4E7C-979E-695D55FC8C7E Q27302281-ABF56C79-49A5-4217-ACB2-40B1334E2724 Q28075761-433991BA-AA1C-44D6-A8EF-ABEA07792826 Q28242019-41DD4D0E-1E5E-4449-8ABE-0396CB67AC29 Q28395484-ECED3424-1D59-4B70-90D6-E5FC96C2BB6A Q28511458-D8300E6A-58F9-4ED3-B8C5-BE52AE548764 Q28743906-33E40665-F842-41C7-9DE9-3E8652493486 Q30225510-D37C704B-44FC-40EF-8AEC-EC9B1FE535F6 Q30438623-FC5CA66C-2E6C-4769-8BB4-FD298E52F23B Q33356511-24497A72-ADA3-4D79-B4EF-DE109087E4D5 Q33606675-6AA55686-99C6-49DB-B02A-B702ECACFE50 Q33750026-E1CA61B1-A142-4191-879A-83BAB865C476 Q33849571-F1CB622B-D0FB-40FD-A2B8-44F4C01AB047 Q33898712-2E669568-36A4-4678-B0F1-67B620260441 Q34096129-51C1D54B-F6CA-4841-BE3D-81E22F98ACEC Q34113473-2671E6BE-D549-4BFC-8FF8-A8D2DCBCD910 Q34161642-E5201C73-EF8C-478D-B2F1-5F2708317FBB Q34478300-2E490EA2-1BD0-4383-8C5D-B6F9F8A226E9 Q34490681-F86683BF-1414-43A8-B2C5-9C34D28E1C9B Q34562526-DEE02BF9-2271-4F01-BFD7-198E74AE1042 Q34568565-57739DBC-DD87-4694-A107-DEBF89E7B47B Q34965706-DA0C55AE-F3EB-4CF8-AEBE-74E5C23EE595 Q35023623-992A6088-6C82-4508-A36A-27775A719877 Q35108072-AEE69758-146A-4F0E-9F8E-586CDC02F2B5 Q35676646-F8E6A8FF-1BF2-4415-B7CF-EA8F49C69EA3 Q35683548-3940C760-7405-4363-B522-D7A64B5419ED Q35977371-18B31FAE-F015-481C-BA73-1EDD467F7EDE Q35997577-F8CE5907-063A-4778-B786-530F533B8AC3 Q36188413-64BBD633-6AF4-45AF-8ECA-85B7E629380E Q36216417-5C908540-63FB-4C4B-9B44-36F52424E7A0 Q36303818-BCFC8BC8-4FB5-4637-BE5D-5F382D8B8B50 Q36446984-2B97EDFA-BEB5-4060-B34F-DBFC6B8FB427 Q36449203-B2CC0FAF-4B1B-4F38-888C-6EF1C1C3389D Q36623486-3DFCFDBE-401C-4B5E-81DD-D8A4A064692C Q36640056-EDE7410C-AD8A-408A-81B9-E075525402A0 Q36978755-CF7B5F7A-F7AD-4C21-9468-993DD9A3BC98

P2860

The CHEK2 gene and inherited breast cancer susceptibility

http://www.wikidata.org/entity/Q28265315

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

The CHEK2 gene and inherited breast cancer susceptibility

@ast

The CHEK2 gene and inherited breast cancer susceptibility

@en

The CHEK2 gene and inherited breast cancer susceptibility

@nl

type

label

The CHEK2 gene and inherited breast cancer susceptibility

@ast

The CHEK2 gene and inherited breast cancer susceptibility

@en

The CHEK2 gene and inherited breast cancer susceptibility

@nl

prefLabel

The CHEK2 gene and inherited breast cancer susceptibility

@ast

The CHEK2 gene and inherited breast cancer susceptibility

@en

The CHEK2 gene and inherited breast cancer susceptibility

@nl

P1433

Q28265315-504C8F79-9460-49C9-A11D-A2CFF7AF3DD8

P1476

Q28265315-65B021FE-CF64-4B71-9946-C21E78B695FC

P2093

Q28265315-DE429721-9225-4A8F-BE8C-F14BD5FAAAD3

P2860

Q28265315-03786783-ABC3-4AB2-B932-1FF1D052810C

Q28265315-0732D4B2-1C35-4DAD-BCE4-7A44CED91B9D

Q28265315-0D27E149-812C-42DA-B180-32E60042EBE9

Q28265315-0F746359-55E2-4B52-A9DD-69CF8DEF43BC

Q28265315-0FCC09A8-9F52-422C-9D94-D8F9797D9819

Q28265315-14C887DA-1A62-40BA-B440-D073DFF6FBE4

Q28265315-163E2526-851E-4474-AC7D-FE02BA49EFA2

Q28265315-1E285D2D-E09C-42AE-9336-4B5B17D17568

Q28265315-2323C052-0484-4CDB-8B19-82F58D121122

Q28265315-2B9E562E-E463-42C9-BB67-CA4B81BB6838

P2888

Q28265315-C2735D30-8A1E-4F13-A404-439F3BA4AAFD

P304

Q28265315-CC6F1E74-A155-4651-85E7-7C428B664B94

P31

Q28265315-CC7F03F2-12B6-4A4E-818F-85CDEF5E8726

P3181

Q28265315-ED3844AC-227A-458A-9C0E-EF8652139BE7

P356

Q28265315-62D39F22-225D-41AF-8988-F0DBBEBFE8C3

P407

Q28265315-6CEB69C3-FBD6-44E7-B8C0-B565C6CE3577

P433

Q28265315-B63DA3F2-38C4-4E86-85A4-603599083F20

P478

Q28265315-7979DF58-BBE8-4579-B9C1-B3CE497B5B0F

P50

Q28265315-A3BB3D38-C3C9-434A-902F-D25D1D33B078

P577

Q28265315-5393B5F7-23FF-426A-8688-F65658DC58A5

P5875

Q28265315-60B9BDB2-4F72-40D9-A107-4A0BA90A0B03

P6179

Q28265315-3000C07A-E192-4A5F-8F1D-372FF1D3D77C

P698

Q28265315-9EF8B377-1C45-42F3-B294-56AD345063B2

P3181

P356

P1433

P1476

The CHEK2 gene and inherited breast cancer susceptibility

@en

P2093

J Bartek

http://www.w3.org/2001/XMLSchema#string

P2860

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Frequency of CHEK2 mutations in a population based, case-control study of breast cancer in young women

Frequency of CHEK2*1100delC in New York breast cancer cases and controls

Mutation analysis of the CHK2 gene in breast carcinoma and other cancers

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

Cell-cycle checkpoints and cancer

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

P2888

P304

5912-9

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3169825

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/SJ.ONC.1209877

http://www.w3.org/2001/XMLSchema#string

P407

P433

43

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P50

Heli Nevanlinna

P577

2006-09-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6795127

http://www.w3.org/2001/XMLSchema#string

P6179

1025485247

http://www.w3.org/2001/XMLSchema#string

P698

16998506

http://www.w3.org/2001/XMLSchema#string