Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene - Test2 - elhamkhani - TriplyDB

Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene

Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene

http://www.wikidata.org/entity/Q28242019

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Alternative cyclin D1 splice forms differentially regulate the DNA damage response Current Management Strategies in Breast Cancer by Targeting Key Altered Molecular Players Nucleases in homologous recombination as targets for cancer therapy Targeting DNA damage response in cancer therapy Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair Combined genetic and nutritional risk models of triple negative breast cancer Double-strand break repair and colorectal cancer: gene variants within 3' UTRs and microRNAs binding as modulators of cancer risk and clinical outcome Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function Hereditary breast cancer: ever more pieces to the polygenic puzzle.Suppression of Akt-mTOR pathway-a novel component of oncogene induced DNA damage response barrier in breast tumorigenesis RAD50 targeting impairs DNA damage response and sensitizes human breast cancer cells to cisplatin therapy Expanding the genetic basis of copy number variation in familial breast cancer.PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[α]indene Derivative in Lung Cancer Cells Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer.Serological analysis of SEREX-defined medullary breast carcinoma-associated antigens.XRCC3 and RAD51 expression are associated with clinical factors in breast cancer.Crystal structure of the Mre11-Rad50-ATPγS complex: understanding the interplay between Mre11 and Rad50 Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia Hodgkin lymphoma risk: role of genetic polymorphisms and gene-gene interactions in DNA repair pathways.Growing recognition of the role for rare missense substitutions in breast cancer susceptibility RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families Genes associated with recurrence of hepatocellular carcinoma: integrated analysis by gene expression and methylation profiling INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells Polymorphisms in poly (ADP-ribose) polymerase-1 (PARP1) promoter and 3' untranslated region and their association with PARP1 expression in breast cancer patients.DNA repair genes implicated in triple negative familial non-BRCA1/2 breast cancer predisposition.Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancer.Panel of SEREX-defined antigens for breast cancer autoantibodies profile detection.Gene-panel sequencing and the prediction of breast-cancer risk.Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer.Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment Impact of race and tumor subtype on second malignancy risk in women with breast cancer.Immunohistochemical analysis of medullary breast carcinoma autoantigens in different histological types of breast carcinomas.Circadian-disruption-induced gene expression changes in rodent mammary tissues.Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer.Molecular genetics of breast and ovarian cancer: recent advances and clinical implications Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers.

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Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene

http://www.wikidata.org/entity/Q28242019

description

2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008年の論文

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2008年論文

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Aberrations of the MRE11-RAD50 ...... ilial cancer-predisposing gene

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Aberrations of the MRE11-RAD50 ...... ilial cancer-predisposing gene

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Aberrations of the MRE11-RAD50 ...... ilial cancer-predisposing gene

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Aberrations of the MRE11-RAD50 ...... ilial cancer-predisposing gene

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Aberrations of the MRE11-RAD50 ...... ilial cancer-predisposing gene

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Aberrations of the MRE11-RAD50 ...... ilial cancer-predisposing gene

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J.MOLONC.2008.09.007

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Molecular Oncology

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Lenka Oplustilova

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Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

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Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

Human CtIP promotes DNA end resection

Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)

Histopathological features of breast tumours in BRCA1, BRCA2 and mutation-negative breast cancer families.

Relationship of patients' age to histopathological features of breast tumours in BRCA1 and BRCA2 and mutation-negative breast cancer families.

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

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