BET domain co-regulators in obesity, inflammation and cancer - Test2 - elhamkhani - TriplyDB

BET domain co-regulators in obesity, inflammation and cancer

BET domain co-regulators in obesity, inflammation and cancer

http://www.wikidata.org/entity/Q28269301

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Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA Strategically targeting MYC in cancer Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics Mechanisms of epigenetic regulation of leukemia onset and progression Brd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetes Chromatin targeting drugs in cancer and immunity Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer Cells Chromatin signatures of cancer Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains Crystal Structure of the Gamma-2 Herpesvirus LANA DNA Binding Domain Identifies Charged Surface Residues Which Impact Viral Latency 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading The emerging role of epigenetics in pulmonary arterial hypertension: an important avenue for clinical trials (2015 Grover Conference Series)Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?H2A.Z: a molecular rheostat for transcriptional control Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection Targeting bromodomains: epigenetic readers of lysine acetylation Functions of BET proteins in erythroid gene expression Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein A Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the Complex The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy Retroviral DNA Integration Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer.Drug Discovery Targeting Bromodomain-Containing Protein 4.The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.Privileged diazepine compounds and their emergence as bromodomain inhibitors.Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice.BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma Bromodomain 4 protein is a predictor of survival for urothelial carcinoma of bladder.Inhibition of BET bromodomain targets genetically diverse glioblastoma Molecular mechanisms of retroviral integration site selection.BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.BET bromodomain inhibitors: a patent review.Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

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BET domain co-regulators in obesity, inflammation and cancer

http://www.wikidata.org/entity/Q28269301

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2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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BET domain co-regulators in obesity, inflammation and cancer

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Nature Reviews Cancer

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BET domain co-regulators in obesity, inflammation and cancer

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P2860

Structure and ligand of a histone acetyltransferase bromodomain

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells

Selective inhibition of BET bromodomains

Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression

Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4

Identification of a polymorphic, neuron-specific chromatin remodeling complex

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA

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