Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
about
The NEDD8 modification pathway in plantsThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancersMyeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent processSuppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53Regulation of nucleolar signalling to p53 through NEDDylation of L11Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA bindingRibosomal proteins are targets for the NEDD8 pathwayFBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activityE2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationp53 isoforms can regulate p53 transcriptional activity.Regulation of cellular response to oncogenic and oxidative stress by Seladin-1NEDD8 acts as a 'molecular switch' defining the functional selectivity of VHLStructural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1Dysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosisThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyStructural basis for the function of DCN-1 in protein Neddylationp53 Acetylation: Regulation and ConsequencesUbiquitylation, neddylation and the DNA damage responseMyeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modificationMDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activityThe ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditionsTRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation.HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerizedTbata modulates thymic stromal cell proliferation and thymus functionMDM2 and MDMX: Alone and together in regulation of p53NEDD8 ultimate buster-1 regulates the abundance of TRF1 at telomeres by promoting its proteasomal degradationModes of p53 regulationp53 ubiquitination: Mdm2 and beyondUbiquitin and ubiquitin-like proteins as multifunctional signalsMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Regulation of parkin and PINK1 by neddylation.Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer.Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast.Regulation of Ubiquitin Enzymes in the TGF-β Pathway.Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity.Posttranslational modification of p53: cooperative integrators of function
P2860
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P2860
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@ast
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@en
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@nl
type
label
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@ast
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@en
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@nl
prefLabel
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@ast
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@en
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@nl
P50
P3181
P1433
P1476
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
@en
P2093
Dimitris P Xirodimas
Mark K Saville
P3181
P356
10.1016/J.CELL.2004.06.016
P407
P577
2004-07-09T00:00:00Z