Central tolerance: learning self-control in the thymus - Test2 - elhamkhani - TriplyDB

Central tolerance: learning self-control in the thymus

Central tolerance: learning self-control in the thymus

http://www.wikidata.org/entity/Q28275215

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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility Transcriptional regulation by AIRE: molecular mechanisms of central tolerance Regulation of the Adaptive Immune Response by the IκB Family Protein Bcl-3 Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease TGF-β: guardian of T cell function Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors High-Density Lipoproteins: Nature's Multifunctional Nanoparticles Tumor neoantigens: building a framework for personalized cancer immunotherapy TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex Regulation of CD8+ T cell development by thymus-specific proteasomes Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP.The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study.Engineering higher affinity T cell receptors using a T cell display system.Immunological tolerance and tumor rejection in embryo-aggregated chimeric mice - lessons for tumor immunity.Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura.Regulation of T cell development and activation by creatine kinase B.Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death.Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice Attenuated Listeria monocytogenes: a powerful and versatile vector for the future of tumor immunotherapy.Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strain Requirement for deoxycytidine kinase in T and B lymphocyte development.Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression Stromal reengineering to treat pancreas cancer Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.Cutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset.The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter Antigen-specific immune reactions to ischemic stroke.Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanisms Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirpα+ dendritic cells: a murine model.Kruppel-like factor 2 is required for trafficking but not quiescence in postactivated T cells

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Central tolerance: learning self-control in the thymus

http://www.wikidata.org/entity/Q28275215

description

2005 nî lūn-bûn

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2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Central tolerance: learning self-control in the thymus

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Central tolerance: learning self-control in the thymus

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Central tolerance: learning self-control in the thymus

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type

label

Central tolerance: learning self-control in the thymus

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Central tolerance: learning self-control in the thymus

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Central tolerance: learning self-control in the thymus

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prefLabel

Central tolerance: learning self-control in the thymus

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Central tolerance: learning self-control in the thymus

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Central tolerance: learning self-control in the thymus

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Nature Reviews Immunology

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Central tolerance: learning self-control in the thymus

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Troy A Baldwin

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Subcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domain

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

Chromosomal clustering of genes controlled by the aire transcription factor.

Positional cloning of the APECED gene

The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

Projection of an immunological self shadow within the thymus by the aire protein

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2642976

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10.1038/NRI1707

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10

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Kristin A. Hogquist

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1016624839

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16200080

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