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A genome-wide association study identifies novel risk loci for type 2 diabetes

A genome-wide association study identifies novel risk loci for type 2 diabetes

http://www.wikidata.org/entity/Q28287727

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The diploid genome sequence of an individual human Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus Data and theory point to mainly additive genetic variance for complex traits A genome-wide association study of the metabolic syndrome in Indian Asian men Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation Structural Properties of Gene Promoters Highlight More than Two Phenotypes of Diabetes Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities. Background Document to the ESHG recommendations on genetic testing and common disorders Personal history of diabetes, genetic susceptibility to diabetes, and risk of brain glioma: a pooled analysis of observational studies Is replication the gold standard for validating genome-wide association findings?Systems medicine: the future of medical genomics and healthcare Fine mapping versus replication in whole-genome association studies Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus Rfx6 directs islet formation and insulin production in mice and humans Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme.Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7 Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function Ubiquitin is a novel substrate for human insulin-degrading enzyme TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes Evidence that the gene encoding insulin degrading enzyme influences human lifespan Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis Genetics and visceral leishmaniasis: of mice and man Association between a literature-based genetic risk score and cardiovascular events in women Variations in DNA elucidate molecular networks that cause disease A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose Variants in MTNR1B influence fasting glucose levels.Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3 The role of genetics in susceptibility to diabetic retinopathy Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study Epigenetics: a molecular link between environmental factors and type 2 diabetes

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A genome-wide association study identifies novel risk loci for type 2 diabetes

http://www.wikidata.org/entity/Q28287727

description

2007 nî lūn-bûn

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2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

@zh-hant

2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

A genome-wide association study identifies novel risk loci for type 2 diabetes

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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type

label

A genome-wide association study identifies novel risk loci for type 2 diabetes

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A genome-wide association study identifies novel risk loci for type 2 diabetes

@en

A genome-wide association study identifies novel risk loci for type 2 diabetes

@nl

prefLabel

A genome-wide association study identifies novel risk loci for type 2 diabetes

@ast

A genome-wide association study identifies novel risk loci for type 2 diabetes

@en

A genome-wide association study identifies novel risk loci for type 2 diabetes

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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Alexandre Belisle

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Alexey V Pshezhetsky

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Barry I Posner

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Daniel Vincent

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David Meyre

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David Serre

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Ghislain Rocheleau

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Guillaume Charpentier

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Johan Rung

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Lishuang Shen

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scholarly article

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188007

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10.1038/NATURE05616

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David Joseph Balding

Alexandre Montpetit

Beverley Balkau

Philippe Froguel

Thomas J. Hudson

Constantin Polychronakos

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2007-02-22T00:00:00Z

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genome-wide association study

type-2 diabetes