Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice
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mTORC1 signaling activates NRF1 to increase cellular proteasome levelsCoordinated regulation of protein synthesis and degradation by mTORC1Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymesInduction of Herpud1 expression by ER stress is regulated by Nrf1p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibitionMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseRegulating the 20S proteasome ubiquitin-independent degradation pathway.SKN-1/Nrf, a new unfolded protein response factor?Liver glycerol permeability and aquaporin-9 are dysregulated in a murine model of Non-Alcoholic Fatty Liver Disease.Discovery of an NRF1-specific inducer from a large-scale chemical library using a direct NRF1-protein monitoring system.The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expressionLipid-mediated regulation of SKN-1/Nrf in response to germ cell absence.SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion.Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma.The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival.Zhang & Manning replyProtective Effects of Combined Selenium and Punica granatum Treatment on Some Inflammatory and Oxidative Stress Markers in Arsenic-Induced Hepatotoxicity in Rats.Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.
P2860
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P2860
Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice
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2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@ast
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@en
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@nl
type
label
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@ast
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@en
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@nl
prefLabel
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@ast
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@en
Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@nl
P2093
P2860
P921
P3181
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Nuclear factor-erythroid 2-rel ...... m stress and steatosis in mice
@en
P2093
Candy S Lee
Daniel V Ho
Jefferson Y Chan
P2860
P304
P3181
P356
10.1111/FEBS.12350
P407
P577
2013-08-01T00:00:00Z