Discovery, structure and biological activities of the cyclotides
about
Cyclotide structure-activity relationships: qualitative and quantitative approaches linking cytotoxic and anthelmintic activity to the clustering of physicochemical forcesA continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae)CyBase: a database of cyclic protein sequence and structureGetting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsAn unusual helix-turn-helix protease inhibitory motif in a novel trypsin inhibitor from seeds of Veronica (Veronica hederifolia L.)Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug ScaffoldDespite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding ModesSolution structure of the circular γ-domain analog from the wheat metallothionein E(c)-1Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxinsConserved structural and sequence elements implicated in the processing of gene-encoded circular proteinsCycloviolacin O2 (CyO2) suppresses productive infection and augments the antiviral efficacy of nelfinavir in HIV-1 infected monocytic cells.Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1.A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.Knottin cyclization: impact on structure and dynamics.Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I.Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinisCyclotides, a promising molecular scaffold for peptide-based therapeutics.Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptorsLysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activityMolecular dynamics exploration of poration and leaking caused by Kalata B1 in HIV-infected cell membrane compared to host and HIV membranesIdentification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides.Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin.The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric poresPredSTP: a highly accurate SVM based model to predict sequential cystine stabilized peptides.Host-defense activities of cyclotides.Cyclotides, a novel ultrastable polypeptide scaffold for drug discoveryPlant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae.CyBase: a database of cyclic protein sequences and structures, with applications in protein discovery and engineeringThe two-step biosynthesis of cyclic peptides from linear precursors in a member of the plant family Caryophyllaceae involves cyclization by a serine protease-like enzymeGlobal cyclotide adventure: a journey dedicated to the discovery of circular peptides from flowering plants.Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions.Design and therapeutic applications of cyclotides.Ribosomal synthesis of backbone macrocyclic peptides.Natural products with antischistosomal activity.Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways.Plant cystine-knot peptides: pharmacological perspectives.Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies.High-performance computational analysis and peptide screening from databases of cyclotides from poaceae.De novo molecular modeling and biophysical characterization of Manduca sexta eclosion hormone.Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif
P2860
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P2860
Discovery, structure and biological activities of the cyclotides
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Discovery, structure and biological activities of the cyclotides
@ast
Discovery, structure and biological activities of the cyclotides
@en
Discovery, structure and biological activities of the cyclotides
@nl
type
label
Discovery, structure and biological activities of the cyclotides
@ast
Discovery, structure and biological activities of the cyclotides
@en
Discovery, structure and biological activities of the cyclotides
@nl
prefLabel
Discovery, structure and biological activities of the cyclotides
@ast
Discovery, structure and biological activities of the cyclotides
@en
Discovery, structure and biological activities of the cyclotides
@nl
P2093
P356
P1476
Discovery, structure and biological activities of the cyclotides
@en
P2093
Jason Mulvenna
Manuel R Plan
Manuela Trabi
P304
P356
10.2174/1389203043379512
P407
P577
2004-10-01T00:00:00Z