Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
about
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instabilityDiffering patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNAThe FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cellsDNA polymerase delta is required for human mismatch repair in vitroHuman Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repairEmbryonic stem cells and somatic cells differ in mutation frequency and typeMSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patensRates of spontaneous mutationInteraction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatinSpontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPaseMutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female miceMicrosatellite instability in colorectal cancerDeficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningMolecular keys to speciation: DNA polymorphism and the control of genetic exchange in enterobacteriaOverexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugsDNA mismatch repair: molecular mechanism, cancer, and ageingMismatch repair deficiency associated with overexpression of the MSH3 geneTwo modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability.Parameters determining the efficiency of gene targeting in the moss Physcomitrella patens.Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesisManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerMouse models for the discovery of colorectal cancer driver genesModeling the study of DNA damage responses in miceAntimutator variants of DNA polymerasesSuppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington’s DiseaseRequirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae.Replication past O(6)-methylguanine by yeast and human DNA polymerase eta.The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs.'Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes.Novel mutations in the RAD3 and SSL1 genes perturb genome stability by stimulating recombination between short repeats in Saccharomyces cerevisiae.Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agentsMechanisms and consequences of somatic mosaicism in humansRepair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cellsMismatch repair gene expression in malignant lymphoproliferative disorders of B-cell originPathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling?Mechanisms and functions of DNA mismatch repairCharacterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2DNA replication fidelity and cancerBcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activity
P2860
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P2860
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@ast
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@en
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@nl
type
label
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@ast
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@en
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@nl
prefLabel
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@ast
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@en
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@nl
P2093
P3181
P1433
P1476
Inactivation of the mouse Msh2 ...... , and predisposition to cancer
@en
P2093
P304
P3181
P356
10.1016/0092-8674(95)90319-4
P407
P577
1995-07-28T00:00:00Z