Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells
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Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cellsHighlight: BRCA1 and BRCA2 proteins in breast cancerEmbryonic stem cells and somatic cells differ in mutation frequency and typeMSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patensInvolvement of nucleotide excision and mismatch repair mechanisms in double strand break repairMitotic homologous recombination maintains genomic stability and suppresses tumorigenesisGenetic steps of mammalian homologous repair with distinct mutagenic consequencesMlh1 mediates tissue-specific regulation of mitotic recombinationProteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.Human MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells.Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.Responsiveness of CPT-11 in respect to hMLH1 and hMSH2 protein expression in the primary colorectal cancer.Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells.High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6.Twisted epithelial-to-mesenchymal transition promotes progression of surviving bladder cancer T24 cells with hTERT-dysfunction.Homologous recombination in human telomerase-positive and ALT cells occurs with the same frequency.Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting.Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair.AID and mismatch repair in antibody diversification.Genome destabilization by homologous recombination in the germ lineExtensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaksBCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instability.Genetic exchange between homeologous sequences in mammalian chromosomes is averted by local homology requirements for initiation and resolution of recombination.Spontaneous mitotic homologous recombination at an enhanced yellow fluorescent protein (EYFP) cDNA direct repeat in transgenic mice.Mismatch repair during homologous and homeologous recombinationInterchromosomal crossover in human cells is associated with long gene conversion tracts.RECQ1 plays a distinct role in cellular response to oxidative DNA damage.Telomerase activity in colorectal cancer, prognostic factor and implications in the microsatellite instability pathway.BaxΔ2 is a novel bax isoform unique to microsatellite unstable tumorsAccurate homologous recombination is a prominent double-strand break repair pathway in mammalian chromosomes and is modulated by mismatch repair protein Msh2.The role of Drosophila mismatch repair in suppressing recombination between diverged sequencesThe PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response.The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repairA Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiaeMSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils.TALEN-based gene correction for epidermolysis bullosa.Biallelic mutation of MSH2 in primary human cells is associated with sensitivity to irradiation and altered RAD51 foci kinetics.Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.
P2860
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P2860
Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells
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2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Repair of double-strand breaks ...... pair-defective mammalian cells
@ast
Repair of double-strand breaks ...... pair-defective mammalian cells
@en
Repair of double-strand breaks ...... pair-defective mammalian cells
@nl
type
label
Repair of double-strand breaks ...... pair-defective mammalian cells
@ast
Repair of double-strand breaks ...... pair-defective mammalian cells
@en
Repair of double-strand breaks ...... pair-defective mammalian cells
@nl
prefLabel
Repair of double-strand breaks ...... pair-defective mammalian cells
@ast
Repair of double-strand breaks ...... pair-defective mammalian cells
@en
Repair of double-strand breaks ...... pair-defective mammalian cells
@nl
P2860
P3181
P1476
Repair of double-strand breaks ...... pair-defective mammalian cells
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.21.8.2671-2682.2001
P407
P577
2001-04-01T00:00:00Z