Rational methods for the selection of diverse screening compounds
about
Rational approaches to improving selectivity in drug designHit identification and optimization in virtual screening: practical recommendations based on a critical literature analysisVirtual Screening Approaches towards the Discovery of Toll-Like Receptor ModulatorsFirst-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosisSystematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetineAllosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2Synthesis and Evaluation of a 2,11-Cembranoid-Inspired LibraryDevelopment and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells.Epigenetic assays for chemical biology and drug discovery.Capture and exploration of sample quality data to inform and improve the management of a screening collection.Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening.Chemical genetics.Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products.Redox-neutral α-oxygenation of amines: reaction development and elucidation of the mechanism.Selecting, Acquiring, and Using Small Molecule Libraries for High-Throughput Screening.Divergent synthesis of biflavonoids yields novel inhibitors of the aggregation of amyloid β (1-42).Synthetic molecules: helping to unravel plant signal transduction.In silico tools used for compound selection during target-based drug discovery and development.Design of a general-purpose European compound screening library for EU-OPENSCREEN.Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS.Objective, Quantitative, Data-Driven Assessment of Chemical Probes.Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase-TPX2 protein-protein interaction.Discovery of Key Physicochemical, Structural, and Spatial Properties of RNA-Targeted Bioactive Ligands.Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling.Advances in the Development of Shape Similarity Methods and Their Application in Drug Discovery
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P2860
Rational methods for the selection of diverse screening compounds
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Rational methods for the selection of diverse screening compounds
@ast
Rational methods for the selection of diverse screening compounds
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Rational methods for the selection of diverse screening compounds
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type
label
Rational methods for the selection of diverse screening compounds
@ast
Rational methods for the selection of diverse screening compounds
@en
Rational methods for the selection of diverse screening compounds
@nl
prefLabel
Rational methods for the selection of diverse screening compounds
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Rational methods for the selection of diverse screening compounds
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Rational methods for the selection of diverse screening compounds
@nl
P2860
P3181
P356
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Rational methods for the selection of diverse screening compounds
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P2093
Ashok R Venkitaraman
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P304
P3181
P356
10.1021/CB100420R
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P577
2011-03-18T00:00:00Z